The mechanisms and efficacy of photobiomodulation therapy for arthritis: a comprehensive review

R Zhang, J Qu - International Journal of Molecular Sciences, 2023 - mdpi.com
Rheumatoid arthritis (RA) and osteoarthritis (OA) have a significant impact on the quality of
life of patients around the world, causing significant pain and disability. Furthermore, the …

Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review

F Salehpour, S Gholipour-Khalili… - Reviews in the …, 2020 - degruyter.com
The application of photobiomodulation therapy (PBMT) for neuronal stimulation is studied in
different animal models and in humans, and has shown to improve cerebral metabolic …

Pretreatment with kaempferol attenuates microglia-mediate neuroinflammation by inhibiting MAPKs–NF–κB signaling pathway and pyroptosis after secondary spinal …

Z Liu, X Yao, B Sun, W Jiang, C Liao, X Dai… - Free Radical Biology …, 2021 - Elsevier
Spinal cord injury (SCI) is a devastating injury that characterized by oxidative stress and
inflammatory response. Kaempferol is reported to be an anti-neuroinflammation in …

Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3

S Chen, J Ye, X Chen, J Shi, W Wu, W Lin… - Journal of …, 2018 - Springer
Background Microglial polarization with M1/M2 phenotype shifts and the subsequent
neuroinflammatory responses are vital contributing factors for spinal cord injury (SCI) …

Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats

X Wang, X Li, X Zuo, Z Liang, T Ding, K Li, Y Ma… - Journal of …, 2021 - Springer
Background Neurotoxic microglia and astrocytes begin to activate and participate in
pathological processes after spinal cord injury (SCI), subsequently causing severe …

Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: Mechanisms of light therapy for Alzheimer's disease

YV Stepanov, I Golovynska, R Zhang… - Alzheimer's research & …, 2022 - Springer
Background Low-intensity light can decelerate neurodegenerative disease progression and
reduce amyloid β (Aβ) levels in the cortex, though the cellular and molecular mechanisms by …

Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPσ receptors promotes a beneficial inflammatory response following spinal cord injury

S Dyck, H Kataria, A Alizadeh, KT Santhosh… - Journal of …, 2018 - Springer
Background Traumatic spinal cord injury (SCI) results in upregulation of chondroitin sulfate
proteoglycans (CSPGs) by reactive glia that impedes repair and regeneration in the spinal …

“Photobiomics”: can light, including photobiomodulation, alter the microbiome?

A Liebert, B Bicknell, DM Johnstone… - … , and laser surgery, 2019 - liebertpub.com
Objective: The objective of this review is to consider the dual effects of microbiome and
photobiomodulation (PBM) on human health and to suggest a relationship between these …

Photobiomodulation attenuates neurotoxic polarization of macrophages by inhibiting the notch1-HIF-1α/NF-κB signalling pathway in mice with spinal cord injury

Y Ma, P Li, C Ju, X Zuo, X Li, T Ding, Z Liang… - Frontiers in …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a catastrophic disease with a complex pathogenesis that includes
inflammation, oxidative stress, and glial scar formation. Macrophages are the main …

Photobiomodulation promotes repair following spinal cord injury by regulating the transformation of A1/A2 reactive astrocytes

X Wang, Z Zhang, Z Zhu, Z Liang, X Zuo, C Ju… - Frontiers in …, 2021 - frontiersin.org
After spinal cord injury (SCI), reactive astrocytes can be classified into two distinctive
phenotypes according to their different functions: neurotoxic (A1) astrocytes and …