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[HTML][HTML] Erythropoietin (EPO) as a key regulator of erythropoiesis, bone remodeling and endothelial transdifferentiation of multipotent mesenchymal stem cells (MSCs) …
AS Tsiftsoglou - Cells, 2021 - mdpi.com
Human erythropoietin (EPO) is an N-linked glycoprotein consisting of 166 aa that is
produced in the kidney during the adult life and acts both as a peptide hormone and …
produced in the kidney during the adult life and acts both as a peptide hormone and …
Belzutifan: first approval
ED Deeks - Drugs, 2021 - Springer
Belzutifan (Welireg™) is an oral small molecule inhibitor of hypoxia-inducible factor (HIF)-2α
being developed by Peloton Therapeutics for the treatment of solid tumours, including renal …
being developed by Peloton Therapeutics for the treatment of solid tumours, including renal …
The transcriptional and regulatory identity of erythropoietin producing cells
Erythropoietin (Epo) is the master regulator of erythropoiesis and oxygen homeostasis.
Despite its physiological importance, the molecular and genomic contexts of the cells …
Despite its physiological importance, the molecular and genomic contexts of the cells …
[HTML][HTML] The role of PI3K/AKT and MAPK signaling pathways in erythropoietin signalization
Erythropoietin (EPO) is a glycoprotein cytokine known for its pleiotropic effects on various
types of cells and tissues. EPO and its receptor EPOR trigger signaling cascades …
types of cells and tissues. EPO and its receptor EPOR trigger signaling cascades …
Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: an emerging therapeutic strategy for type 1 diabetes
I Camaya, S Donnelly, B O'Brien - Journal of Diabetes, 2022 - Wiley Online Library
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of the
insulin‐producing β‐cells within the pancreas. Islet transplantation represents one cure; …
insulin‐producing β‐cells within the pancreas. Islet transplantation represents one cure; …
Erythropoietin regulation of red blood cell production: from bench to bedside and back
More than 50 years of efforts to identify the major cytokine responsible for red blood cell
(RBC) production (erythropoiesis) led to the identification of erythropoietin (EPO) in 1977 …
(RBC) production (erythropoiesis) led to the identification of erythropoietin (EPO) in 1977 …
Influence of COVID-19 on cerebrovascular disease and its possible mechanism
H Fan, X Tang, Y Song, P Liu… - … Disease and Treatment, 2020 - Taylor & Francis
The global spread of COVID-19 has caused a substantial societal burden and become a
major global public health issue. The COVID-19 elderly population with hypertension …
major global public health issue. The COVID-19 elderly population with hypertension …
Silk fibroin/collagen/hydroxyapatite scaffolds obtained by 3D printing technology and loaded with recombinant human erythropoietin in the reconstruction of alveolar …
H Liu, C Wang, X Sun, C Zhan, Z Li, L Qiu… - ACS biomaterials …, 2022 - ACS Publications
The fast osteogenesis of the large alveolar fossa and the maintenance of the height of the
alveolar ridge after tooth extraction have always been a clinical challenge. Therefore, this …
alveolar ridge after tooth extraction have always been a clinical challenge. Therefore, this …
Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis
The erythroblastic island (EBI), composed of a central macrophage surrounded by maturing
erythroblasts, is the erythroid precursor niche. Despite numerous studies, its precise …
erythroblasts, is the erythroid precursor niche. Despite numerous studies, its precise …
[HTML][HTML] Hypoxia-inducible factors signaling in osteogenesis and skeletal repair
Q Qin, Y Liu, Z Yang, M Aimaijiang, R Ma… - International journal of …, 2022 - mdpi.com
Sufficient oxygen is required to maintain normal cellular and physiological function, such as
a creature's development, breeding, and homeostasis. Lately, some researchers have …
a creature's development, breeding, and homeostasis. Lately, some researchers have …