Human hepatitis B virus (HBV) is the prototype of a family of small DNA viruses that
productively infect hepatocytes, the major cell of the liver, and replicate by reverse …

Hepatitis B virus (HBV), an enveloped partially double-stranded DNA virus, is a widespread
human pathogen responsible for more than 250 million chronic infections worldwide …

Among numerous established human hepatoma cell lines, none has been shown
susceptible to hepatitis B virus (HBV) infection. We describe here a cell line, called HepaRG …

The hepatoblastoma cell line Hep G2 was transfected with a plasmid carrying the gene that
confers resistance to G418 and four 5'-3'tandem copies of the hepatitis B virus (HBV) …

We report the development and isolation of a cell line, termed HepAD38, that replicates
human hepatitis B virus (HBV) under conditions that can be regulated with tetracycline. In …

Hepatitis B virus (HBV) particles are generated by budding of preformed cytoplasmic
nucleocapsids into endoplasmic reticulum (ER) membranes containing the three viral …

GP73 is a novel type II Golgi membrane protein of unknown function that is expressed in the
hepatocytes of patients with adult giant-cell hepatitis (Gene 2000; 249: 53-65). Its expression …

To correlate the hepatitis B virus P gene with the enzymatic activities predicted to participate
in hepadnavirus reverse transcription, a series of P gene mutants containing missense …

In vitro hepatocyte models represent very useful systems in both fundamental research and
various application areas. Primary hepatocytes appear as the closest model for the liver in …

Hepatitis B virus (HBV) is a major human pathogen that chronically infects≈ 350 million
people, causing liver disease and liver cancer. HBV virions bud into an endoplasmic …