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Coacervate droplets for synthetic cells
The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …
features of living cells–have experienced a real boom in the past decade. While many efforts …
[HTML][HTML] Coacervates as models of membraneless organelles
Coacervates are condensed liquid-like droplets, usually formed with oppositely charged
polymeric molecules. They have been studied extensively in colloid and interface science …
polymeric molecules. They have been studied extensively in colloid and interface science …
Protocells: Milestones and recent advances
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …
Self-assembly of stabilized droplets from liquid–liquid phase separation for higher-order structures and functions
Dynamic microscale droplets produced by liquid–liquid phase separation (LLPS) have
emerged as appealing biomaterials due to their remarkable features. However, the …
emerged as appealing biomaterials due to their remarkable features. However, the …
Plant cell-inspired membranization of coacervate protocells with a structured polysaccharide layer
Y Ji, Y Lin, Y Qiao - Journal of the American Chemical Society, 2023 - ACS Publications
The design of compartmentalized colloids that exhibit biomimetic properties is providing
model systems for develo** synthetic cell-like entities (protocells). Inspired by the cell …
model systems for develo** synthetic cell-like entities (protocells). Inspired by the cell …
ATP‐responsive and ATP‐fueled self‐assembling systems and materials
Adenosine triphosphate (ATP) is a central metabolite that plays an indispensable role in
various cellular processes, from energy supply to cell‐to‐cell signaling. Nature has …
various cellular processes, from energy supply to cell‐to‐cell signaling. Nature has …
Synthetic cells revisited: Artificial cell construction using polymeric building blocks
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …
potential as tools to advance the understanding of fundamental biological processes. The …
Signal processing and generation of bioactive nitric oxide in a model prototissue
The design and construction of synthetic prototissues from integrated assemblies of artificial
protocells is an important challenge for synthetic biology and bioengineering. Here we …
protocells is an important challenge for synthetic biology and bioengineering. Here we …
Triggerable protocell capture in nanoparticle-caged coacervate microdroplets
Controlling the dynamics of mixed communities of cell-like entities (protocells) provides a
step toward the development of higher-order cytomimetic behaviors in artificial cell …
step toward the development of higher-order cytomimetic behaviors in artificial cell …
Peptide-based coacervate protocells with cytoprotective metal–phenolic network membranes
Protocells have garnered considerable attention from cell biologists, materials scientists,
and synthetic biologists. Phase-separating coacervate microdroplets have emerged as a …
and synthetic biologists. Phase-separating coacervate microdroplets have emerged as a …