Single-cell metabolomics with mass spectrometry enables a large variety of metabolites to
be simultaneously detected from individual cells, without any preselection or labelling, to …

Studying cell heterogeneity can provide a deeper understanding of biological activities, but
appropriate studies cannot be performed using traditional bulk analysis methods. The …

Single-cell analysis is critical to revealing cell-to-cell heterogeneity that would otherwise be
lost in ensemble analysis. Detailed lipidome characterization for single cells is still far from …

Cell manipulation is the foundation of biochemical studies, which demands user-friendly,
multifunctional and precise tools. Based on flow confinement principles, open microfluidics …

Metabolism is at the cornerstone of all cellular functions and mounting evidence of its
deregulation in different diseases emphasizes the importance of a comprehensive …

Single cell analysis has drawn increasing interest from the research community due to its
capability to interrogate cellular heterogeneity, allowing refined tissue classification and …

Cellular heterogeneity is generally overlooked in infectious diseases. In this study, we
investigated host cell heterogeneity during infection with Trypanosoma cruzi (T. cruzi) …

Single-cell-based genomics and transcriptomics analysis have revealed substantial cellular
heterogeneity among seemingly identical cells. Knowledge of the cellular heterogeneity at …

life science, clinical diagnostics, drug development, etc. Recent years have witnessed the
emergence of innovative analytical methods with high sensitivity and spatial-temporal …

Cell–cell interactions are critical for transmitting signals among cells and maintaining their
normal functions from the single-cell level to tissues. In cancer studies, interactions between …