Prostate cancer (PCa) is the second most frequently diagnosed cancer in men. Despite the
significant progress in cancer diagnosis and treatment over the last few years, the approach …

The highly heterogenous nature of colorectal cancer can significantly hinder its early and
accurate diagnosis, eventually contributing to high mortality rates. The adenoma-carcinoma …

Background This study focuses on the role of lysosomal trafficking in prostate cancer, given
the essential role of lysosomes in cellular homoeostasis. Methods Lysosomal motility was …

Prostate cancer (PCa) development and progression relies on the programming of glucose
and lipid metabolism, and this involves alterations in androgen receptor expression and …

Simple Summary A novel biomarker panel (Appl1, Sortilin and Syndecan-1) was
demonstrated as a strong independent predictor for both clinical and biochemical …

The diagnosis of prostate cancer using histopathology is reliant on the accurate
interpretation of prostate tissue sections. Current standards rely on the assessment of …

The presence of intraductal carcinoma of the prostate (IDCP) correlates with late-stage
disease and poor outcomes for patients with prostatic adenocarcinoma, but the accurate and …

Membrane trafficking, a fundamental cellular process encompassing the transport of
molecules to specific organelles, endocytosis at the plasma membrane and protein …

Membrane trafficking and organelle contact sites are important for regulating cell
metabolism and survival; processes often deregulated in cancer. Prostate cancer is the …

Simple Summary This study acknowledges the challenges in melanoma diagnosis and the
need for new technology that aids clinical decision making. Biomarkers that can accurately …