RANKL/RANK/OPG pathway: a mechanism involved in exercise‐induced bone remodeling

M Tobeiha, MH Moghadasian, N Amin… - BioMed research …, 2020 - Wiley Online Library
Bones as an alive organ consist of about 70% mineral and 30% organic component. About
200 million people are suffering from osteopenia and osteoporosis around the world. There …

Exercise and longevity

V Gremeaux, M Gayda, R Lepers, P Sosner, M Juneau… - Maturitas, 2012 - Elsevier
Aging is a natural and complex physiological process influenced by many factors, some of
which are modifiable. As the number of older individuals continues to increase, it is …

Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading

L You, S Temiyasathit, P Lee, CH Kim, P Tummala… - Bone, 2008 - Elsevier
Bone has the ability to adjust its structure to meet its mechanical environment. The prevailing
view of bone mechanobiology is that osteocytes are responsible for detecting and …

The roles of exercise in bone remodeling and in prevention and treatment of osteoporosis

Y Yuan, X Chen, L Zhang, J Wu, J Guo, D Zou… - Progress in Biophysics …, 2016 - Elsevier
With a rapid increase in the aging population, osteoporosis has become a global health
problem. Although anti-resorption and anabolic drugs are available, osteoporosis cannot be …

Effects of resistance and aerobic exercise on physical function, bone mineral density, OPG and RANKL in older women

EA Marques, F Wanderley, L Machado, F Sousa… - Experimental …, 2011 - Elsevier
This study compared the effects of a resistance training protocol and a moderate-impact
aerobic training protocol on bone mineral density (BMD), physical ability, serum …

[HTML][HTML] Mechanoregulation analysis of bone formation in tissue engineered constructs requires a volumetric method using time-lapsed micro-computed tomography

JK Griesbach, FA Schulte, GN Schädli, M Rubert… - Acta biomaterialia, 2024 - Elsevier
Bone can adapt its microstructure to mechanical loads through mechanoregulation of the
(re) modeling process. This process has been investigated in vivo using time-lapsed micro …

The response of bone to mechanical loading and disuse: fundamental principles and influences on osteoblast/osteocyte homeostasis

TM Skerry - Archives of biochemistry and biophysics, 2008 - Elsevier
Bone's response to increased or reduced loading/disuse is a feature of many clinical
circumstances, and our daily life, as habitual activities change. However, there are several …

Osteocyte-mediated mechanical response controls osteoblast differentiation and function

HVV Buck, JP Stains - Frontiers in Physiology, 2024 - frontiersin.org
Low bone mass is a pervasive global health concern, with implications for osteoporosis,
frailty, disability, and mortality. Lifestyle factors, including sedentary habits, metabolic …

[HTML][HTML] Osteosarcoma and metastasis associated bone degradation—a tale of osteoclast and malignant cell cooperativity

KS Nørregaard, HJ Jürgensen, H Gårdsvoll… - International Journal of …, 2021 - mdpi.com
Cancer-induced bone degradation is part of the pathological process associated with both
primary bone cancers, such as osteosarcoma, and bone metastases originating from, eg …

Response of bone mineral density, inflammatory cytokines, and biochemical bone markers to a 32-week combined loading exercise programme in older men and …

EA Marques, J Mota, JL Viana, D Tuna… - Archives of gerontology …, 2013 - Elsevier
This study examines the effects of 32 weeks of exercise training on balance, lower-extremity
muscle strength, bone mineral density (BMD) and serum levels of bone metabolism and …