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Endophytic fungi: key insights, emerging prospects, and challenges in natural product drug discovery
P Tiwari, H Bae - Microorganisms, 2022 - mdpi.com
Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …
Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …
secondary metabolites to support industrial production and mitigate over-exploitation of …
Fungal endophytes as efficient sources of plant-derived bioactive compounds and their prospective applications in natural product drug discovery: Insights, avenues …
Fungal endophytes are well-established sources of biologically active natural compounds
with many producing pharmacologically valuable specific plant-derived products. This …
with many producing pharmacologically valuable specific plant-derived products. This …
Contribution of endophytes towards improving plant bioactive metabolites: a rescue option against red-ta** of medicinal plants
Medicinal plants remain a valuable source for natural drug bioprospecting owing to their
multi-target spectrum. However, their use as raw materials for novel drug synthesis has been …
multi-target spectrum. However, their use as raw materials for novel drug synthesis has been …
Microbial endophytes: application towards sustainable agriculture and food security
Microbial endophytes are ubiquitous and exist in each recognised plant species reported till
date. Within the host plant, the entire community of microbes lives non-invasively within the …
date. Within the host plant, the entire community of microbes lives non-invasively within the …
[PDF][PDF] Endophytic fungi residing in medicinal plants have the ability to produce the same or similar pharmacologically active secondary metabolites as their hosts.
A Venieraki, M Dimou, P Katinakis - 2017 - sciendo.com
Medicinal plants have been used for thousands of years in folk medicines and still are used
for their health benefits. In our days medicinal plants are exploited for the isolation of plant …
for their health benefits. In our days medicinal plants are exploited for the isolation of plant …
The potential use of fungal co-culture strategy for discovery of new secondary metabolites
S Xu, M Li, Z Hu, Y Shao, J Ying, H Zhang - Microorganisms, 2023 - mdpi.com
Fungi are an important and prolific source of secondary metabolites (SMs) with diverse
chemical structures and a wide array of biological properties. In the past two decades …
chemical structures and a wide array of biological properties. In the past two decades …
Fungal endophytes: an accessible source of bioactive compounds with potential anticancer activity
Endophytes either be bacteria, fungi, or actinomycetes colonize inside the tissue of host
plants without showing any immediate negative effects on them. Among numerous natural …
plants without showing any immediate negative effects on them. Among numerous natural …
Characterization and antitumor activity of camptothecin from endophytic fungus Fusarium solani isolated from Camptotheca acuminate
X Ran, G Zhang, S Li, J Wang - African health sciences, 2017 - ajol.info
Background: Camptothecin (CPT) is a potent drug against cancers, originally from plants.
The endophytic fungi could produce the secondary metabolite same as the host and is used …
The endophytic fungi could produce the secondary metabolite same as the host and is used …
Production and bioprocessing of camptothecin from Aspergillus terreus, an endophyte of Cestrum parqui, restoring their biosynthetic potency by Citrus limonum peel …
ASA El-Sayed, NM George, A Abou-Elnour… - Microbial Cell …, 2023 - Springer
The metabolic potency of fungi as camptothecin producer elevates their prospective use as
an industrial platform for commercial production, however, the loss of camptothecin …
an industrial platform for commercial production, however, the loss of camptothecin …