Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation
(DNAm) patterns. Age and sex, two major risk factors for AD, are also known to largely affect …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex …

Alzheimer disease (AD) is a common neurodegenerative disease with a late onset. It is
critical to identify novel blood-based DNA methylation biomarkers to better understand the …

Background People with neurodegenerative disorders show diverse clinical syndromes,
genetic heterogeneity, and distinct brain pathological changes, but studies report overlap …

Epigenome-wide association studies of Alzheimer's disease have highlighted
neuropathology-associated DNA methylation differences, although existing studies have …

Background Growing evidence shows that epigenetic modifications play a role in
Alzheimer's disease (AD). We performed an epigenome-wide association study (EWAS) to …

Background Identifying biomarkers associated with Alzheimer's disease (AD) progression
may enable patient enrichment and improve clinical trial designs. Epigenome-wide …

Background Growing evidence has demonstrated that DNA methylation (DNAm) plays an
important role in Alzheimer's disease (AD) and that DNAm differences can be detected in the …

To better understand DNA methylation in Alzheimer's disease (AD) from both mechanistic
and biomarker perspectives, we performed an epigenome-wide meta-analysis of blood DNA …