Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

[PDF][PDF] Noninvasive, quantitative assessment of liver fat by MRI‐PDFF as an endpoint in NASH trials

C Caussy, SB Reeder, CB Sirlin, R Loomba - Hepatology, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver
disease worldwide, and the progressive form of this condition, nonalcoholic steatohepatitis …

Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning

Y Liu, N Basty, B Whitcher, JD Bell, EP Sorokin… - Elife, 2021 - elifesciences.org
Cardiometabolic diseases are an increasing global health burden. While socioeconomic,
environmental, behavioural, and genetic risk factors have been identified, a better …

[HTML][HTML] Noninvasive evaluation of nonalcoholic fatty liver disease: Current evidence and practice

JH Zhou, JJ Cai, ZG She, HL Li - World journal of gastroenterology, 2019 - ncbi.nlm.nih.gov
With the increasing number of individuals with diabetes and obesity, nonalcoholic fatty liver
disease (NAFLD) is becoming increasingly prevalent, affecting one-quarter of adults …

Linearity, bias, and precision of hepatic proton density fat fraction measurements by using MR imaging: a meta-analysis

T Yokoo, SD Serai, A Pirasteh, MR Bashir, G Hamilton… - Radiology, 2018 - pubs.rsna.org
Purpose To determine the linearity, bias, and precision of hepatic proton density fat fraction
(PDFF) measurements by using magnetic resonance (MR) imaging across different field …

MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: clinical trials to clinical practice

PS Dulai, CB Sirlin, R Loomba - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of
chronic liver disease, and its prevalence is rising worldwide. The occurrence of non …

[HTML][HTML] Radiologic evaluation of nonalcoholic fatty liver disease

SS Lee, SH Park - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a frequent cause of chronic liver diseases,
ranging from simple steatosis to nonalcoholic steatohepatitis (NASH)-related liver cirrhosis …

Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy

SB Reeder, I Cruite, G Hamilton… - Journal of magnetic …, 2011 - Wiley Online Library
Hepatic steatosis is characterized by abnormal and excessive accumulation of lipids within
hepatocytes. It is an important feature of diffuse liver disease, and the histological hallmark …

[PDF][PDF] Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials

M Noureddin, J Lam, MR Peterson, M Middleton… - …, 2013 - Wiley Online Library
The magnetic resonance imaging–estimated proton density fat fraction (MRI‐PDFF) is a
novel imaging‐based biomarker that allows fat map** of the entire liver, whereas the …

Quantitative MRI and spectroscopy of bone marrow

DC Karampinos, S Ruschke… - Journal of Magnetic …, 2018 - Wiley Online Library
Bone marrow is one of the largest organs in the human body, enclosing adipocytes,
hematopoietic stem cells, which are responsible for blood cell production, and mesenchymal …