The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

Focused ultrasound is a platform technology capable of eliciting a wide range of biological
responses with high spatial precision deep within the body. Although focused ultrasound is …

Focused ultrasound (FUS) is a powerful tool for noninvasive modulation of deep brain
activity with promising therapeutic potential for refractory epilepsy; however, tools for …

The proximity and association of cerebrospinal fluid (CSF) and the intrathecal (IT) space with
deep targets in the central nervous system (CNS) parenchyma makes IT injection an …

Background and objective: Transcranial focused ultrasound (tFUS) has emerged as a new
non-invasive brain stimulation (NIBS) modality, with its exquisite ability to reach deep brain …

Transcranial focused ultrasound (tFUS) has emerged as a new mode of non-invasive brain
stimulation (NIBS), with its exquisite spatial precision and capacity to reach the deep regions …

Transport of interstitial fluid and solutes plays a critical role in clearing metabolic waste from
the brain. Transcranial application of focused ultrasound (FUS) has been shown to promote …

Background Cerebrospinal fluid (CSF) flow is crucial for brain homeostasis and its
dysfunction is highly associated with neurodegenerative diseases. Restoring CSF …

Cells in the brain are surrounded by extracellular space (ECS), which forms porous nets and
interconnected routes for molecule transportation. Our view of brain ECS has changed from …

Cerebrospinal fluid (CSF) is crucial for maintaining neuronal homeostasis, providing
nutrition, and removing metabolic waste from the brain. However, the relationship between …