Improving outcomes of first‐episode psychosis: an overview
Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …
clinical burden. There is thus an urgent clinical and societal need for improving those …
Altering the course of schizophrenia: progress and perspectives
MJ Millan, A Andrieux, G Bartzokis… - Nature reviews Drug …, 2016 - nature.com
Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …
genetic and environmental causes has considerably improved, and their relationship to …
EPA guidance on assessment of negative symptoms in schizophrenia
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …
brought about by the increased awareness that they interfere severely with real-life …
How effective are cognitive behavior therapies for major depression and anxiety disorders? A meta‐analytic update of the evidence
We report the current best estimate of the effects of cognitive behavior therapy (CBT) in the
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
treatment of major depression (MDD), generalized anxiety disorder (GAD), panic disorder …
Heterogeneity of psychosis risk within individuals at clinical high risk: a meta-analytical stratification
Importance Individuals can be classified as being at clinical high risk (CHR) for psychosis if
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …
A critique of the “ultra‐high risk” and “transition” paradigm
The transdiagnostic expression of psychotic experiences in common mental disorder
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
Development and validation of a clinically based risk calculator for the transdiagnostic prediction of psychosis
Importance The overall effect of At Risk Mental State (ARMS) services for the detection of
individuals who will develop psychosis in secondary mental health care is undetermined …
individuals who will develop psychosis in secondary mental health care is undetermined …
At risk or not at risk? A meta‐analysis of the prognostic accuracy of psychometric interviews for psychosis prediction
An accurate detection of individuals at clinical high risk (CHR) for psychosis is a prerequisite
for effective preventive interventions. Several psychometric interviews are available, but their …
for effective preventive interventions. Several psychometric interviews are available, but their …
Multimodal machine learning workflows for prediction of psychosis in patients with clinical high-risk syndromes and recent-onset depression
Importance Diverse models have been developed to predict psychosis in patients with
clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining …
clinical high-risk (CHR) states. Whether prediction can be improved by efficiently combining …
The clinical high-risk state for psychosis (CHR-P), version II
P Fusar-Poli - Schizophrenia bulletin, 2017 - academic.oup.com
Abstract The Clinical High-Risk state for psychosis (CHR-P) paradigm was introduced about
2 decades ago. Over this period of time accumulating knowledge has been gained …
2 decades ago. Over this period of time accumulating knowledge has been gained …