The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous …

Chemokines have fundamental roles in regulating immune and inflammatory responses,
primarily through their control of leukocyte migration and localization. The biological …

Cancer is considered a life-threatening disease, and several factors are involved in its
development. Chemokines are small proteins that physiologically exert pivotal roles in …

The chemokine receptor CCR7 and its ligands CCL19 and CCL21 control a diverse array of
migratory events in adaptive immune function. Most prominently, CCR7 promotes homing of …

Chemerin was isolated as the natural ligand of the G protein-coupled receptor ChemR23.
Chemerin acts as a chemotactic factor for leukocyte populations expressing ChemR23 …

Chemerin is a small chemotactic protein originally identified as the natural ligand of
CMKLR1. More recently, two other receptors, GPR1 and CCRL2, have been reported to bind …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Among heterogeneous primary tumors of the central nervous system (CNS), gliomas are the
most frequent type, with glioblastoma multiforme (GBM) characterized with the worst …

Chemokine-like receptor 1 (CMKLR1), also known as ChemR23, and chemokine (C–C
motif) receptor-like 2 (CCRL2) are 7-transmembrane receptors that were cloned in the late …