Emerging insights into hypothalamic‐pituitary‐gonadal axis regulation and interaction with stress signalling

A Acevedo‐Rodriguez, AS Kauffman… - Journal of …, 2018 - Wiley Online Library
Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal
(HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and …

Sex differences in circadian timing systems: implications for disease

M Bailey, R Silver - Frontiers in neuroendocrinology, 2014 - Elsevier
Virtually every eukaryotic cell has an endogenous circadian clock and a biological sex.
These cell-based clocks have been conceptualized as oscillators whose phase can be reset …

Inputs and outputs of the mammalian circadian clock

AN Starnes, JR Jones - Biology, 2023 - mdpi.com
Simple Summary In mammals, circadian rhythms in nearly all behaviors and physiological
processes are controlled by the suprachiasmatic nucleus, a collection of neurons in the …

The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges

CA Christian, SM Moenter - Endocrine reviews, 2010 - academic.oup.com
Ovarian steroids normally exert homeostatic negative feedback on GnRH release. During
sustained exposure to elevated estradiol in the late follicular phase of the reproductive cycle …

Circadian clock function in the mammalian ovary

MT Sellix - Journal of biological rhythms, 2015 - journals.sagepub.com
Rhythmic events in the female reproductive system depend on the coordinated and
synchronized activity of multiple neuroendocrine and endocrine tissues. This coordination is …

Sex differences in daily timekee** and circadian clock circuits

DAM Joye, JA Evans - Seminars in cell & developmental biology, 2022 - Elsevier
The circadian system regulates behavior and physiology in many ways important for health.
Circadian rhythms are expressed by nearly every cell in the body, and this large system is …

Evidence for suprachiasmatic vasopressin neurones innervating kisspeptin neurones in the rostral periventricular area of the mouse brain: regulation by oestrogen

B Vida, L Deli, E Hrabovszky… - Journal of …, 2010 - Wiley Online Library
In rodents, a circadian signal from the suprachiasmatic nucleus (SCN) is essential for the pro‐
oestrous surge of gonadotrophin‐releasing hormone (GnRH), which, in turn, induces …

Modulation of circadian rhythms through estrogen receptor signaling

KM Hatcher, SE Royston… - European Journal of …, 2020 - Wiley Online Library
Circadian rhythms are physiological and behavioral processes that exhibit a 24‐hr cycle.
These daily rhythms are essential for living organisms to align their behavior and physiology …

Sex hormones, sleep, and memory: interrelationships across the adult female lifespan

YA Harrington, JM Parisi, D Duan… - Frontiers in Aging …, 2022 - frontiersin.org
As the population of older adults grows, so will the prevalence of aging-related conditions,
including memory impairments and sleep disturbances, both of which are more common …

Estrogen receptor β expression in the mouse forebrain: age and sex differences

DG Zuloaga, KL Zuloaga, LR Hinds… - Journal of …, 2014 - Wiley Online Library
Estrogen receptors regulate multiple brain functions, including stress, sexual, and memory‐
associated behaviors as well as controlling neuroendocrine and autonomic function. During …