Mitochondria are organelles with a highly dynamic ultrastructure maintained by a delicate
equilibrium between its fission and fusion rates. Understanding the factors influencing this …

The maintenance of cellular identity requires continuous adaptation to environmental
changes. This process is particularly critical for stem cells, which need to preserve their …

Crosstalk mechanisms between pericytes, endothelial cells, and astrocytes preserve
integrity and function of the blood-brain-barrier (BBB) under physiological conditions. Long …

Background In recent years, copper complexes have gradually become the focus of
potential anticancer drugs due to their available redox properties and low toxicity. In this …

The adult mammalian central nervous system (CNS) has very limited regenerative capacity
upon neural injuries or under degenerative conditions. In recent years, however, significant …

The core transcriptional network regulating stem cell self-renewal and pluripotency remains
an intense area of research. Increasing evidence indicates that modified regulation of basic …

Erythropoiesis is the most robust cellular differentiation and proliferation system, with a
production of∼ 2× 1011 cells per day. In this fine-tuned process, the hematopoietic stem …

The mitochondrial inner membrane proteins OMA1 and OPA1 belong to the BAX/BAK1‐
dependent apoptotic signaling pathway, which can be regulated by tumor protein p53 and …

Cell reprogramming is thought to be associated with a full metabolic switch from an oxidative-
to a glycolytic-based metabolism. However, neither the dynamics nor the factors controlling …

Abstract Hexavalent chromium [Cr (VI)] is ubiquitous in the environment and is commonly
used in various industrial processes. Clusterin (CLU) is an extracellular chaperone protein …