In order to survive, animals must avoid injury and be able to detect potentially damaging
stimuli via nociceptive mechanisms. If the injury is accompanied by a negative affective …

Chronic pain is a maladaptive neurological disease that remains a major health problem. A
deepening of our knowledge on mechanisms that cause pain is a prerequisite to develo** …

Stress is a common cause of neuropsychiatric disorders, evoking multiple behavioral,
endocrine and neuro-immune deficits. Animal models have been extensively used to …

Sex is an important variable in biomedical research. The zebrafish (Danio rerio) is
increasingly utilized as a powerful new model organism in translational neuroscience and …

The pyrethroid insecticide permethrin is widely used for agricultural and domestic purposes.
Previous data indicated that it acts as a developmental neurotoxicant and can induce …

Pain is an unpleasant, negative emotion and its debilitating effects are complex to manage.
Mammalian models have long dominated research on nociception and pain, but there is …

Terpenes are the most extensive and varied group of naturally occurring compounds mostly
found in plants, including cannabis, and have an array of potential therapeutic benefits for …

Despite the high prevalence of medicinal use and abuse of opioids, their neurobiology and
mechanisms of action are not fully understood. Experimental (animal) models are critical for …

Zebrafish (Danio rerio) have emerged as a powerful model to study the gut microbiome in
the context of human conditions, including hypertension, cardiovascular disease …

Potently affecting human and animal brain and behavior, hallucinogenic drugs have recently
emerged as potentially promising agents in psychopharmacotherapy. Complementing …