The theory of constructed emotion is a systems neuroscience approach to understanding the
nature of emotion. It is also a general theoretical framework to guide hypothesis generation …

Major depressive disorder (MDD) remains the most prevalent mental disorder and a leading
cause of disability, affecting approximately 100 million adults worldwide. The disorder is …

Sleep and the circadian clock are intertwined and have persisted throughout history. The
suprachiasmatic nucleus (SCN) orchestrates sleep by controlling circadian (Process C) and …

Twenty‐four‐hour rhythmicity in physiology and behavior are driven by changes in
neurophysiological activity that vary across the light–dark and rest‐activity cycle. Although …

Introduction Melatonin and its precursor serotonin are neurochemicals that play an important
role in the physiological regulation of mood, sleep, and behavior. Studies have suggested …

Objective Several lines of evidence support a relationship between circadian rhythms
disruption in the onset, course, and maintenance of mental disorders. Despite the study of …

The circadian misalignment of the gut microbiota caused by unusual eating times in adult
animals is related to disease development. However, whether the composition and diurnal …

Background Although disturbances in biological rhythms are closely related to the onset of
major depressive disorder (MDD), they are not commonly assessed in Chinese clinical …

Fish perceive environmental cues through sensory organs like the pineal gland and retina,
and transduce them as internal stimuli to activate an endocrine network known as the brain …

In many medical settings, medications are typically administered in the morning or evening,
aligning with patients' daily routines. This practice does not stem from chronotherapy, which …