The Use of yeast in Biosensing
Yeast has been used as a model for several diseases as it is the simplest unicellular
eukaryote, safe and easy to culture and harbors most of the fundamental processes that are …
eukaryote, safe and easy to culture and harbors most of the fundamental processes that are …
Magic Blue-Initiated SN2-Type Ring Opening of Activated Aziridines: Friedel–Crafts-Type Alkylation of Electron-Rich Arenes/Heteroarenes
A transition metal-free, atom-economical, and highly stereospecific synthetic approach to
Friedel–Crafts-type alkylation of arenes/heteroarenes has been developed. The protocol …
Friedel–Crafts-type alkylation of arenes/heteroarenes has been developed. The protocol …
[HTML][HTML] Ultrasensitive quantification of trace amines based on N-phosphorylation labeling chip 2D LC-QQQ/MS
X Bian, Y Zhang, N Li, M Shi, X Chen, HL Zhang… - Journal of …, 2023 - Elsevier
Trace amines (TAs) are metabolically related to catecholamine and associated with cancer
and neurological disorders. Comprehensive measurement of TAs is essential for …
and neurological disorders. Comprehensive measurement of TAs is essential for …
Trace amine-associated receptor 1 (TAAR1): an emerging therapeutic target for neurodegenerative, neurodevelopmental, and neurotraumatic disorders
S Dalvi, LK Bhatt - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
Trace amines are physiologically active amines present in all organisms. They are
structurally identical to traditional monoamines and are rapidly metabolized by monoamine …
structurally identical to traditional monoamines and are rapidly metabolized by monoamine …
Simvastatin efficiently reduces levels of Alzheimer's amyloid beta in yeast
A large-scale epidemiology study on statins previously showed that simvastatin was unique
among statins in reducing the incidence of dementia. Since amyloid beta (Aβ42) is the …
among statins in reducing the incidence of dementia. Since amyloid beta (Aβ42) is the …
Electrochemical Immunosensor for the Sensitive Detection of Alzheimer's Biomarker Amyloid‐β (1–42) Using the Heme‐amyloid‐β (1–42) Complex as the Signal …
M Ding, Q Shu, N Zhang, C Yan, H Niu, X Li… - …, 2022 - Wiley Online Library
Abstract The amyloid‐β peptide (1–42)(Aβ42) can provide high diagnostic accuracy for the
early diagnosis of Alzheimer's disease (AD). In this study, an immunosensor based on the …
early diagnosis of Alzheimer's disease (AD). In this study, an immunosensor based on the …
[HTML][HTML] Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease
Shifts in the magnitude and nature of gut microbial metabolites have been implicated in
Alzheimer's disease (AD), but the host receptors that sense and respond to these …
Alzheimer's disease (AD), but the host receptors that sense and respond to these …
'The awesome power of yeast'in Alzheimer's disease research
S Dhakal - Microbiology Australia, 2021 - CSIRO Publishing
The difficulties in performing experimental studies related to diseases of the human brain
have fostered a range of disease models from highly expensive and complex animal models …
have fostered a range of disease models from highly expensive and complex animal models …
[HTML][HTML] Genetic reduction of tyramine β hydroxylase suppresses Tau toxicity in a Drosophila model of tauopathy
V Nangia, J O'Connell, K Chopra, Y Qing, C Reppert… - Neuroscience …, 2021 - Elsevier
Tauopathies are a class of neurodegenerative diseases characterized by the abnormal
phosphorylation and accumulation of the microtubule-associated protein, Tau. These …
phosphorylation and accumulation of the microtubule-associated protein, Tau. These …
Effect of Chronic Dolutegravir Administration on the Trace Amine Profile in Wistar Rats
Background Dolutegravir (DTG), an integrase strand inhibitor, is currently used as the first-
line treatment for HIV. Despite relatively poor tissue penetration, the risk of adverse effects in …
line treatment for HIV. Despite relatively poor tissue penetration, the risk of adverse effects in …