Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

[HTML][HTML] Human Studies of Transcranial Ultrasound neuromodulation: A systematic review of effectiveness and safety

C Sarica, JF Nankoo, A Fomenko, TC Grippe… - Brain stimulation, 2022 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is gaining traction as a safe and non-
invasive technique in human studies. There has been a rapid increase in TUS human …

[HTML][HTML] Mechanisms of theta burst transcranial ultrasound induced plasticity in the human motor cortex

YS Oghli, T Grippe, T Arora, T Hoque, G Darmani… - Brain Stimulation, 2023 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is a novel non-invasive brain
stimulation technique with high depth penetrance and spatial resolution. Theta-burst TUS …

Auditory confounds can drive online effects of transcranial ultrasonic stimulation in humans

BR Kop, YS Oghli, TC Grippe, T Nandi, J Lefkes… - Elife, 2024 - elifesciences.org
Transcranial ultrasonic stimulation (TUS) is rapidly emerging as a promising non-invasive
neuromodulation technique. TUS is already well-established in animal models, providing …

Ultrasonic deep brain neuromodulation in acute disorders of consciousness: a proof-of-concept

JA Cain, NM Spivak, JP Coetzee, JS Crone… - Brain sciences, 2022 - mdpi.com
The promotion of recovery in patients who have entered a disorder of consciousness (DOC;
eg, coma or vegetative states) following severe brain injury remains an enduring medical …

Low-intensity focused ultrasound for human neuromodulation

W Legon, A Strohman - Nature Reviews Methods Primers, 2024 - nature.com
Low-intensity focused ultrasound (LIFU) is a potentially transformative form of human non-
invasive neuromodulation that provides millimetre-sized focal volumes combined with …

Recent advances in the use of focused ultrasound as a treatment for epilepsy

E Lescrauwaet, K Vonck, M Sprengers… - Frontiers in …, 2022 - frontiersin.org
Epilepsy affects about 1% of the population. Approximately one third of patients with
epilepsy are drug-resistant (DRE). Resective surgery is an effective treatment for DRE, yet …

[HTML][HTML] Transcranial ultrasound stimulation to human middle temporal complex improves visual motion detection and modulates electrophysiological responses

CR Butler, E Rhodes, J Blackmore, X Cheng, RL Peach… - Brain Stimulation, 2022 - Elsevier
Background Transcranial ultrasound stimulation (TUS) holds promise as a novel technology
for non-invasive neuromodulation, with greater spatial precision than other available …

Transcranial ultrasound stimulation modulates the interhemispheric balance of excitability in human motor cortex

L Ren, Z Zhai, Q **ang, K Zhuo, S Zhang… - Journal of Neural …, 2023 - iopscience.iop.org
Background. Low-intensity transcranial ultrasound stimulation (TUS) could induce both
immediate and long-lasting neuromodulatory effects in human brains. Interhemispheric …

[HTML][HTML] The effect of transcranial ultrasound pulse repetition frequency on sustained inhibition in the human primary motor cortex: A double-blind, sham-controlled …

AK Zadeh, H Raghuram, S Shrestha, M Kibreab… - Brain Stimulation, 2024 - Elsevier
Background Non-invasive brain stimulation techniques such as transcranial magnetic
stimulation and transcranial direct current stimulation hold promise for inducing brain …