Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Background Antibiotic resistance is currently the most serious global threat to the effective
treatment of bacterial infections. Antibiotic resistance has been established to adversely …

The human gut microbiome plays an important role in resisting colonization of the host by
pathogens, but we lack the ability to predict which communities will be protective. We …

Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a major global
pathogen with limited treatment options. No new antibiotic chemical class with activity …

Background Antimicrobial resistance (AMR) represents one of the most crucial threats to
public health and modern health care. Previous studies have identified challenges with …

Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …

Summary Background Lower respiratory infections (LRIs) are a major global contributor to
morbidity and mortality. In 2020–21, non-pharmaceutical interventions associated with the …

Background Antimicrobial resistance (AMR) is a pressing, holistic, and multisectoral
challenge facing contemporary global health. In this study we assessed the associations …

Abstract The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) …

The rise of pan-resistant bacteria is creating an urgent need for structurally novel antibiotics.
Artificial intelligence methods can discover new antibiotics, but existing methods have …