Macrophages in immunoregulation and therapeutics

S Chen, AFUH Saeed, Q Liu, Q Jiang, H Xu… - Signal transduction and …, 2023 - nature.com
Macrophages exist in various tissues, several body cavities, and around mucosal surfaces
and are a vital part of the innate immune system for host defense against many pathogens …

[HTML][HTML] Macrophage-mediated inflammation in skin wound healing

A Hassanshahi, M Moradzad, S Ghalamkari, M Fadaei… - Cells, 2022 - mdpi.com
Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Metabolism of tissue macrophages in homeostasis and pathology

SK Wculek, G Dunphy, I Heras-Murillo… - Cellular & molecular …, 2022 - nature.com
Cellular metabolism orchestrates the intricate use of tissue fuels for catabolism and
anabolism to generate cellular energy and structural components. The emerging field of …

Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes

M Arabpour, A Saghazadeh, N Rezaei - International …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells beneficial in regenerative medicine
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …

Targeting the epigenetic regulation of antitumour immunity

SJ Hogg, PA Beavis, MA Dawson… - Nature reviews Drug …, 2020 - nature.com
Dysregulation of the epigenome drives aberrant transcriptional programmes that promote
cancer onset and progression. Although defective gene regulation often affects oncogenic …

M2b macrophage polarization and its roles in diseases

L Wang, S Zhang, H Wu, X Rong… - Journal of leukocyte …, 2019 - academic.oup.com
Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

Macrophage polarization and its role in the pathogenesis of acute lung injury/acute respiratory distress syndrome

X Chen, J Tang, W Shuai, J Meng, J Feng, Z Han - Inflammation Research, 2020 - Springer
Purpose Macrophages are highly plastic cells. Under different stimuli, macrophages can be
polarized into several different subsets. Two main macrophage subsets have been …

The roles of macrophage polarization in the host immune response to sepsis

X Chen, Y Liu, Y Gao, S Shou, Y Chai - International immunopharmacology, 2021 - Elsevier
Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …

Myeloid-derived suppressor cells coming of age

F Veglia, M Perego, D Gabrilovich - Nature immunology, 2018 - nature.com
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells
generated during a large array of pathologic conditions ranging from cancer to obesity …

[HTML][HTML] Influence of resveratrol on the immune response

L Malaguarnera - Nutrients, 2019 - mdpi.com
Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, mulberries,
peanuts, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the …