Activatable fluorescent probes for real-time imaging-guided tumor therapy

QJ Duan, ZY Zhao, YJ Zhang, L Fu, YY Yuan… - Advanced Drug Delivery …, 2023 - Elsevier
Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Fluorescence-guided surgery

T Nagaya, YA Nakamura, PL Choyke… - Frontiers in …, 2017 - frontiersin.org
Surgical resection of cancer remains an important treatment modality. Despite advances in
preoperative imaging, surgery itself is primarily guided by the surgeon's ability to locate …

Beyond the margins: real-time detection of cancer using targeted fluorophores

RR Zhang, AB Schroeder, JJ Grudzinski… - Nature reviews Clinical …, 2017 - nature.com
Over the past two decades, synergistic innovations in imaging technology have resulted in a
revolution in which a range of biomedical applications are now benefiting from fluorescence …

Global cancer surgery: delivering safe, affordable, and timely cancer surgery

R Sullivan, OI Alatise, BO Anderson, R Audisio… - The lancet …, 2015 - thelancet.com
Surgery is essential for global cancer care in all resource settings. Of the 15· 2 million new
cases of cancer in 2015, over 80% of cases will need surgery, some several times. By 2030 …

Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging

AV DSouza, H Lin, ER Henderson… - … of biomedical optics, 2016 - spiedigitallibrary.org
There is growing interest in using fluorescence imaging instruments to guide surgery, and
the leading options for open-field imaging are reviewed here. While the clinical fluorescence …

NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green

C Egloff-Juras, L Bezdetnaya, G Dolivet… - International journal of …, 2019 - Taylor & Francis
Surgery is the frontline treatment for a large number of cancers. The objective of these
excisional surgeries is the complete removal of the primary tumor with sufficient safety …

Peptide-based agents for cancer treatment: current applications and future directions

NTT Nhàn, T Yamada, KH Yamada - International Journal of Molecular …, 2023 - mdpi.com
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …

A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application

M Garland, JJ Yim, M Bogyo - Cell chemical biology, 2016 - cell.com
The Precision Medicine Initiative aims to use advances in basic and clinical research to
develop therapeutics that selectively target and kill cancer cells. Under the same doctrine of …

Use of ultrasmall core-shell fluorescent silica nanoparticles for image-guided sentinel lymph node biopsy in head and neck melanoma: a nonrandomized clinical trial

DK Zanoni, HE Stambuk, B Madajewski… - JAMA Network …, 2021 - jamanetwork.com
Importance Sentinel lymph node (SLN) map** agents approved for current surgical
practice lack sufficient brightness and target specificity for high-contrast, sensitive nodal …

Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

IP Santos, EM Barroso, TCB Schut, PJ Caspers… - Analyst, 2017 - pubs.rsc.org
Oncological applications of Raman spectroscopy have been contemplated, pursued, and
developed at academic level for at least 25 years. Published studies aim to detect pre …