Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data

RAS Salman, J Frantzias, RJ Lee, PD Lyden… - The Lancet …, 2018 - thelancet.com
Background Intracerebral haemorrhage growth is associated with poor clinical outcome and
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …

Intracerebral haemorrhage

AI Qureshi, AD Mendelow, DF Hanley - The Lancet, 2009 - thelancet.com
Intracerebral haemorrhage is an important public health problem leading to high rates of
death and disability in adults. Although the number of hospital admissions for intracerebral …

Preclinical and clinical research on inflammation after intracerebral hemorrhage

J Wang - Progress in neurobiology, 2010 - Elsevier
Intracerebral hemorrhage (ICH) is one of the most lethal stroke subtypes. Despite the high
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage in Adults: 2007 Update: A Guideline from the American Heart Association/American Stroke …

J Broderick, S Connolly, E Feldmann, D Hanley… - Stroke, 2007 - ahajournals.org
Purpose—The aim of this statement is to present current and comprehensive
recommendations for the diagnosis and treatment of acute spontaneous intracerebral …

Acute stroke biomarkers: are we there yet?

M Dagonnier, GA Donnan, SM Davis… - Frontiers in …, 2021 - frontiersin.org
Background: Distinguishing between stroke subtypes and knowing the time of stroke onset
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …

Inflammation after intracerebral hemorrhage

J Wang, S Doré - Journal of Cerebral Blood Flow & …, 2007 - journals.sagepub.com
Intracerebral hemorrhage (ICH) is a devastating clinical event without effective therapies.
Increasing evidence suggests that inflammatory mechanisms are involved in the …

Stroke biomarkers: progress and challenges for diagnosis, prognosis, differentiation, and treatment

AK Saenger, RH Christenson - Clinical chemistry, 2010 - academic.oup.com
Background: Stroke is a devastating condition encompassing a wide range of
pathophysiological entities that include thrombosis, hemorrhage, and embolism. Current …

Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

K Arai, G **, D Navaratna, EH Lo - The FEBS journal, 2009 - Wiley Online Library
Pathophysiologic responses in brain after stroke are highly complex. Thus far, a singular
focus on saving neurons alone has not revealed any clinically effective neuroprotectants. To …

Hematoma expansion in intracerebral hemorrhage: an update on prediction and treatment

Z Li, M You, C Long, R Bi, H Xu, Q He, B Hu - Frontiers in neurology, 2020 - frontiersin.org
Intracerebral hemorrhage (ICH) is the most lethal type of stroke, but there is no specific
treatment. After years of effort, neurologists have found that hematoma expansion (HE) is a …

Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage

J Wang, SE Tsirka - Brain, 2005 - academic.oup.com
Intracerebral haemorrhage (ICH) is an acute neurological disorder without effective
treatment. Mechanisms of acute brain injury after ICH remain to be clarified. Although a few …