Cross-kingdom small RNA trafficking between hosts and microbes modulates gene
expression in the interacting partners during infection. However, whether other RNAs are …

Summary mRNA function is influenced by modifications that modulate canonical nucleobase
behavior. We show that a single modification mediates distinct impacts on mRNA translation …

In all species, ribosomes synthesize proteins by faithfully decoding messenger RNA (mRNA)
nucleotide sequences using aminoacyl-tRNA substrates. Current knowledge of the …

Previously we showed that 2D template matching (2DTM) can be used to localize
macromolecular complexes in images recorded by cryogenic electron microscopy (cryo-EM) …

Despite whole-genome sequencing (WGS), many cases of single-gene disorders remain
unsolved, impeding diagnosis and preventative care for people whose disease-causing …

The single-stranded RNA genome of SARS-CoV-2 is highly structured. Numerous helical
stem–loop structures interrupted by mismatch motifs are present in the functionally important …

Candida albicans is a widespread commensal fungus with substantial pathogenic potential
and steadily increasing resistance to current antifungal drugs. It is known to be resistant to …

Sharp eyespot is a crucial disease affecting cereal plants, such as bread wheat (Triticum
aestivum) and barley (Hordeum vulgare), and is primarily caused by the pathogenic fungus …

Assembly of functional ribosomal subunits and successfully delivering them to the
translating pool is a prerequisite for protein synthesis and cell growth. In S. cerevisiae, the …

Polyribosomes, the groups of ribosomes simultaneously translating a single mRNA
molecule, are very common in both, prokaryotic and eukaryotic cells. Even in early EM …