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Chediak-higashi syndrome
J Kaplan, I De Domenico… - Current opinion in …, 2008 - journals.lww.com
Although CHS is a rare disease, the Chediak-like family of proteins is providing insight into
the regulation of vesicle trafficking. Understanding the basic mechanisms that govern vesicle …
the regulation of vesicle trafficking. Understanding the basic mechanisms that govern vesicle …
Epstein-Barr virus and human diseases: recent advances in diagnosis
M Okano, GM Thiele, JR Davis… - Clinical microbiology …, 1988 - journals.asm.org
Since the discovery of Epstein-Barr virus (EBV) from a cultured Burkitt's lymphoma cell line
in 1964, the virus has been associated with Burkitt's lymphoma, nasopharyngeal carcinoma …
in 1964, the virus has been associated with Burkitt's lymphoma, nasopharyngeal carcinoma …
The immune response to primary EBV infection: a role for natural killer cells
H Williams, K McAulay, KF Macsween… - British journal of …, 2005 - Wiley Online Library
The role of antigen‐specific CD3+ CD8+ cytotoxic T cells in the control of primary Epstein–
Barr Virus (EBV) infection is well established. However, time is required for the antigen …
Barr Virus (EBV) infection is well established. However, time is required for the antigen …
Analysis of the lysosomal storage disease Chediak–Higashi syndrome
D McVey Ward, GM Griffiths, JC Stinchcombe, J Kaplan - Traffic, 2000 - Wiley Online Library
Chediak–Higashi syndrome (CHS) is a rare autosomal recessive disorder of human, mouse
(beige) and other mammalian species. The same genetic defect was found to result in the …
(beige) and other mammalian species. The same genetic defect was found to result in the …
Chediak—Higashi Syndrome
Y Barak, E Nir - Journal of Pediatric Hematology/Oncology, 1987 - journals.lww.com
The use of cytochemical, electron microscopic, immunofluorescent, and tissue culture
techniques has led to important advances in our understanding of the mechanisms …
techniques has led to important advances in our understanding of the mechanisms …
Genetic Defects in Chediak–Higashi Syndrome and the beige Mouse
RA Spritz - Journal of clinical immunology, 1998 - Springer
Chediak–Higashi syndrome (CHS) is a rare, autosomal recessive, multisystem disorder in
which severe immune deficits are accompanied by abnormalities of pigmentation, blood …
which severe immune deficits are accompanied by abnormalities of pigmentation, blood …
LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
Mutations in the large BEACH domain‐containing protein LYST causes Chediak–Higashi
syndrome. The diagnostic hallmark is enlarged lysosomes and lysosome‐related organelles …
syndrome. The diagnostic hallmark is enlarged lysosomes and lysosome‐related organelles …
The storage pool deficiency in platelets from humans with the Chédiak‐Higashi syndrome: study of six patients
R Apitz‐Castro, MR Cruz, E Ledezma… - British journal of …, 1985 - Wiley Online Library
Functional and biochemical studies of platelets from human Chédiak‐Higashi syndrome
(CHS) are scarce and/or incomplete. In the present report, the aggregation response to a …
(CHS) are scarce and/or incomplete. In the present report, the aggregation response to a …
A review of Epstein-Barr virus infection in patients with immunodeficiency disorders
M Okano, TG Gross - The American journal of the medical sciences, 2000 - Elsevier
ABSTRACT Epstein-Barr virus (EBV), one of 8 known human herpesviruses, infects the vast
majority of mankind and infections are generally subclinical. However, EBV infection has …
majority of mankind and infections are generally subclinical. However, EBV infection has …
Advanced therapeutic and prophylactic strategies for Epstein–Barr virus infection in immunocompromised patients
M Okano, TG Gross - Expert Review of Anti-Infective Therapy, 2007 - Taylor & Francis
Epstein–Barr virus (EBV) is an ubiquitous human herpesvirus. Primary infection is generally
subclinical but in certain circumstances, such as in patients with either hereditary or …
subclinical but in certain circumstances, such as in patients with either hereditary or …