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Recent advances in epilepsy
M Manford - Journal of neurology, 2017 - Springer
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics
and underlying mechanisms, including status epilepticus, drug and surgical treatments …
and underlying mechanisms, including status epilepticus, drug and surgical treatments …
Idiopathic generalized epilepsy: misunderstandings, challenges, and opportunities
The idiopathic generalized epilepsies (IGE) make up a fifth of all epilepsies, but< 1% of
epilepsy research. This skew reflects misperceptions: diagnosis is straightforward …
epilepsy research. This skew reflects misperceptions: diagnosis is straightforward …
Focal abnormalities in idiopathic generalized epilepsy: a critical review of the literature
Conventionally, epilepsy is dichotomized into distinct “focal” and “generalized” categories.
However, many studies have reported so‐called focal features among patients with …
However, many studies have reported so‐called focal features among patients with …
[HTML][HTML] Recent advances in neuroimaging of epilepsy
Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …
and the relationship between pathophysiology, seizure management, and outcomes. This …
Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy
Objective We sought to determine which combination of clinical and
electroencephalography (EEG) characteristics differentiate between an antiseizure …
electroencephalography (EEG) characteristics differentiate between an antiseizure …
Photosensitivity in generalized epilepsies
Photosensitivity, which is the hallmark of photosensitive epilepsy (PSE), is described as an
abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The …
abnormal EEG response to visual stimuli known as a photoparoxysmal response (PPR). The …
Resistance to valproic acid as predictor of treatment resistance in genetic generalized epilepsies
J Gesche, M Khanevski, C Solberg, CP Beier - Epilepsia, 2017 - Wiley Online Library
This study aimed at defining clinical predictors of drug resistance in adults with genetic
generalized epilepsy (GGE) who were treated with a broad spectrum of antiepileptic drugs …
generalized epilepsy (GGE) who were treated with a broad spectrum of antiepileptic drugs …
Neuroimaging in epilepsy
In recent years, the field of neuroimaging has undergone dramatic development.
Specifically, of importance for clinicians and researchers managing patients with epilepsies …
Specifically, of importance for clinicians and researchers managing patients with epilepsies …
Methods and utility of EEG-fMRI in epilepsy
LA van Graan, L Lemieux… - Quantitative imaging in …, 2015 - pmc.ncbi.nlm.nih.gov
Brain activity data in general and more specifically in epilepsy can be represented as a
matrix that includes measures of electrophysiology, anatomy and behaviour. Each of these …
matrix that includes measures of electrophysiology, anatomy and behaviour. Each of these …
Drug resistance in idiopathic generalized epilepsies: Evidence and concepts
J Gesche, CP Beier - Epilepsia, 2022 - Wiley Online Library
Abstract Although approximately 10%–15% of patients with idiopathic generalized epilepsy
(IGE)/genetic generalized epilepsy remain drug‐resistant, there is no consensus or …
(IGE)/genetic generalized epilepsy remain drug‐resistant, there is no consensus or …