Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives

JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

MicroRNAs: pioneering regulators in Alzheimer's disease pathogenesis, diagnosis, and therapy

YB Li, Q Fu, M Guo, Y Du, Y Chen, Y Cheng - Translational Psychiatry, 2024 - nature.com
This article delves into Alzheimer's disease (AD), a prevalent neurodegenerative condition
primarily affecting the elderly. It is characterized by progressive memory and cognitive …

Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases

S Khemka, A Reddy, RI Garcia, M Jacobs… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. Genetic mutations cause a small …

The role of vitamin K in humans: implication in aging and age-associated diseases

DS Popa, G Bigman, ME Rusu - Antioxidants, 2021 - mdpi.com
As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

Pathophysiological aspects and therapeutic armamentarium of Alzheimer's disease: recent trends and future development

BP Dave, YB Shah, KG Maheshwari… - Cellular and Molecular …, 2023 - Springer
Alzheimer's disease (AD) is the primary cause of dementia and is characterized by the death
of brain cells due to the accumulation of insoluble amyloid plaques, hyperphosphorylation of …

Polyphenols as potential metal chelation compounds against Alzheimer's disease

J Lakey-Beitia, AM Burillo, G La Penna… - Journal of …, 2021 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more
than 50 million people worldwide. The pathology of this multifactorial disease is primarily …

Dietary and supplemental long-chain omega-3 fatty acids as moderators of cognitive impairment and Alzheimer's disease

AHR Wood, HF Chappell, MA Zulyniak - European journal of nutrition, 2022 - Springer
Purpose There is an ever-growing body of literature examining the relationship between
dietary omega-3 polyunsaturated fatty acids (ω3 PUFAs) and cerebral structure and function …

[HTML][HTML] The effects of aerobic exercise and transcranial direct current stimulation on cognitive function in older adults with and without cognitive impairment: A …

K Talar, T Vetrovsky, M van Haren, J Négyesi… - Ageing Research …, 2022 - Elsevier
Background Aerobic exercise (AE) may slow age-related cognitive decline. However, such
cognition-sparing effects are not uniform across cognitive domains and studies. Transcranial …

Alzheimer's disease and Alzheimer's disease-related dementias in Hispanics: Identifying influential factors and supporting caregivers

P Rawat, U Sehar, J Bisht, AP Reddy… - Ageing Research Reviews, 2024 - Elsevier
Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD) are the
primary public health concerns in the United States and around the globe. AD/ADRD are …