IOP and glaucoma damage: The essential role of optic nerve head and retinal mechanosensors
There are many unanswered questions on the relation of intraocular pressure to glaucoma
development and progression. IOP itself cannot be distilled to a single, unifying value …
development and progression. IOP itself cannot be distilled to a single, unifying value …
[HTML][HTML] Understanding glaucomatous damage: anatomical and functional data from ocular hypertensive rodent retinas
Glaucoma, the second most common cause of blindness, is characterized by a progressive
loss of retinal ganglion cells and their axons, with a concomitant loss of the visual field …
loss of retinal ganglion cells and their axons, with a concomitant loss of the visual field …
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
LJ Lawson, VH Perry, P Dri, S Gordon - Neuroscience, 1990 - Elsevier
We have examined the distribution of microglia in the normal adult mouse brain using
immunocytochemical detection of the macrophage specific plasma membrane glycoprotein …
immunocytochemical detection of the macrophage specific plasma membrane glycoprotein …
Cell death and control of cell survival in the oligodendrocyte lineage
BA Barres, IK Hart, HSR Coles, JF Burne, JT Voyvodic… - Cell, 1992 - cell.com
Dead cells are observed in many develo** animal tissues, but the causes of these normal
cell deaths are mostly unknown. We show that about 50% of oligodendrocytes normally die …
cell deaths are mostly unknown. We show that about 50% of oligodendrocytes normally die …
Brn3a as a marker of retinal ganglion cells: qualitative and quantitative time course studies in naive and optic nerve–injured retinas
purpose. To characterize Brn3a expression in adult albino rat retinal ganglion cells (RGCs)
in naïve animals and in animals subjected to complete intraorbital optic nerve transection …
in naïve animals and in animals subjected to complete intraorbital optic nerve transection …
Immunohistochemical localization of macrophages and microglia in the adult and develo** mouse brain
VH Perry, DA Hume, S Gordon - Neuroscience, 1985 - Elsevier
Macrophages and microglia in the develo** and adult mouse brain have been identified
by is consistent with the idea that dying neurons and axons provide a stimulus for …
by is consistent with the idea that dying neurons and axons provide a stimulus for …
Regressive events in neurogenesis
WM Cowan, JW Fawcett, DDM O'Leary, BB Stanfield - Science, 1984 - science.org
The development of most regions of the vertebrate nervous system includes a distinct phase
of neuronal degeneration during which a substantial proportion of the neurons initially …
of neuronal degeneration during which a substantial proportion of the neurons initially …
Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning
BA Barres, BE Silverstein, DP Corey, LLY Chun - Neuron, 1988 - cell.com
Two different monoclonal antibodies to the Thy-l antigen, TllD7 and 2Gl2, were used to
purify and characterize retinal ganglion cells from postnatal rat retina. Although Thy-l has …
purify and characterize retinal ganglion cells from postnatal rat retina. Although Thy-l has …
Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a prospective analysis of age-related loss
OBJECTIVE: To investigate age-related changes of the retinal nerve fiber layer (RNFL)
imaged by a spectral-domain optical coherence tomography (OCT). DESIGN: Prospective …
imaged by a spectral-domain optical coherence tomography (OCT). DESIGN: Prospective …
Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex
AJ Blaschke, K Staley, J Chun - Development, 1996 - journals.biologists.com
ABSTRACT A key event in the development of the mammalian cerebral cortex is the
generation of neuronal populations during embryonic life. Previous studies have revealed …
generation of neuronal populations during embryonic life. Previous studies have revealed …