Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

In the drug discovery setting, undesirable ADMET properties of a pharmacophore with good
predictive power obtained after a tedious drug discovery and development process may …

Hydrazones and their derivatives are very important compounds in medicinal chemistry due
to their reported biological activity for the treatment of several diseases, like Alzheimer's …

Herein we report the synthesis of two novel series of 1, 3-thiazole derivatives having a
lipophilic C4-substituent on account of the increasing need for novel and versatile antifungal …

In the context of there being a limited number of clinically approved drugs for the treatment of
Candida sp.-based infections, along with the rapid development of resistance to the existing …

The six new copper (II) coordination compounds [Cu (HL1) Cl2](1),[Cu (HL1) Br2](2),[Cu
(H2O)(L1)(CH3COO)]· 1.75 H2O (3),[Cu (HL2) Cl2](4),[Cu (HL2) Br2](5),[Cu …

Invasive fungal infections are a leading cause of death worldwide. Translating molecular
insights into clinical benefits is challenging because fungal pathogens and their hosts share …

Antimicrobial resistance poses a major threat to global health as the number of efficient
antimicrobials decreases and the number of resistant pathogens rises. Our research group …

Three new copper (II) complexes,[Cu (1, 10‐Phen)(L)](1),[Cu (2, 2′‐Bpy)(L)](2) and [Cu (3,
4‐Lut)(L)](3), where H2L= 2‐[(2, 4‐dihydroxyphenyl) methylidene]‐N‐(prop‐2‐en‐1‐yl) …

This Ph. D. thesis comprises several chapters focused on the synthesis of various
derivatives containing ketene dithioacetal, including thiazole, thiazole hydrazide, and …