Nanotoxicology and in vitro studies: the need of the hour

S Arora, JM Rajwade, KM Paknikar - Toxicology and applied pharmacology, 2012 - Elsevier
Nanotechnology is considered as one of the key technologies of the 21st century and
promises revolution in our world. Objects at nano scale, take on novel properties and …

[HTML][HTML] In vitro approaches to assess the hazard of nanomaterials

JHE Arts, M Hadi, MA Irfan, AM Keene… - Regulatory Toxicology …, 2015 - Elsevier
Abstract The European Centre for Ecotoxicology and Toxicology of Chemicals
(ECETOC)'Nano Task Force'proposes a Decision-making framework for the grou** and …

Interference of engineered nanoparticles with in vitro toxicity assays

A Kroll, MH Pillukat, D Hahn, J Schnekenburger - Archives of toxicology, 2012 - Springer
Accurate in vitro assessment of nanoparticle cytotoxicity requires a careful selection of the
test systems. Due to high adsorption capacity and optical activity, engineered nanoparticles …

Central nervous system toxicity of metallic nanoparticles

X Feng, A Chen, Y Zhang, J Wang… - International journal of …, 2015 - Taylor & Francis
Nanomaterials (NMs) are increasingly used for the therapy, diagnosis, and monitoring of
disease-or drug-induced mechanisms in the human biological system. In view of their small …

The impact of coal mine dust characteristics on pathways to respiratory harm: investigating the pneumoconiotic potency of coals

C Kamanzi, M Becker, M Jacobs, P Konečný… - Environmental …, 2023 - Springer
Exposure to dust from the mining environment has historically resulted in epidemic levels of
mortality and morbidity from pneumoconiotic diseases such as silicosis, coal workers' …

[HTML][HTML] In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

SH Doak, B Manshian, GJS Jenkins, N Singh - Mutation Research/Genetic …, 2012 - Elsevier
There is a pressing requirement to define a hazard identification and risk management
strategy for nanomaterials due to the rapid growth in the nanotechnology industry and their …

Particle-induced artifacts in the MTT and LDH viability assays

AL Holder, R Goth-Goldstein, D Lucas… - Chemical research in …, 2012 - ACS Publications
In vitro testing is a common first step in assessing combustion-generated and engineered
nanoparticle-related health hazards. Commercially available viability assays are frequently …

Functionalized gold nanoparticles for the binding, stabilization, and delivery of therapeutic DNA, RNA, and other biological macromolecules

RK DeLong, CM Reynolds, Y Malcolm… - Nanotechnology …, 2010 - Taylor & Francis
Nanotechnology has virtually exploded in the last few years with seemingly limitless
opportunity across all segments of our society. If gene and RNA therapy are to ever realize …