In the presence of multivalent cations, high molecular weight DNA undergoes a dramatic
condensation to a compact, usually highly ordered toroidal structure. This review begins with …

This paper is in recognition of the 100th birthday of Dr. Herbert Tabor, a true pioneer in the
polyamine field for over 70 years, who served as the editor-in-chief of the Journal of …

Abstract The polyamines spermidine (3+) and spermine (4+) are known to cause a co-
operative intramolecular condensation of T7 or λ phage DNAs in which the DNA assumes a …

Soft matter materials, such as polymers, membranes, proteins, are often electrically charged.
This makes them water soluble, which is of great importance in technological application …

It is generally acknowledged that geometrical and conformational properties of biopolymers
have an important effect on their biochemical behaviour. It is less easily recognized that …

Since the study of the molecular nature of the life cycle of double-stranded DNA
bacteriophages began, the problem of how the chromosome is condensed into the virion …

Intercalation models for the binding of drugs to DNA involve the postulate of drug-induced
local uncoiling of the double helix. Such uncoiling results in removal and reversal of the …

DNA toroids produced by the condensation of λ phage DNA with hexammine cobalt (III)
have been investigated by cryoelectron microscopy. Image resolution obtained by this …

Compaction is the process in which a large DNA molecule undergoes a transition between
an elongated conformation and a very compact form. In nature, DNA compaction occurs to …

Biogenic amines are organic polycations derived from aromatic or cationic amino acids. All
of them have one or more positive charges and a hydrophobic skeleton. Nature has evolved …