Stimuli-responsive ferroptosis for cancer therapy

N Kang, S Son, S Min, H Hong, C Kim, J An… - Chemical Society …, 2023 - pubs.rsc.org
Ferroptosis, an iron-dependent programmed cell death mechanism, is regulated by distinct
molecular pathways of lipid peroxidation caused by intracellular iron supplementation and …

Glutathione-depleting nanomedicines for synergistic cancer therapy

X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …

Electroactive biomaterials and systems for cell fate determination and tissue regeneration: design and applications

Z Liu, X Wan, ZL Wang, L Li - Advanced Materials, 2021 - Wiley Online Library
During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

Rational design in photopharmacology with molecular photoswitches

P Kobauri, FJ Dekker, W Szymanski… - Angewandte Chemie …, 2023 - Wiley Online Library
Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

GSH‐Depleted PtCu3 Nanocages for Chemodynamic‐ Enhanced Sonodynamic Cancer Therapy

X Zhong, X Wang, L Cheng, Y Tang… - Advanced Functional …, 2020 - Wiley Online Library
The ultrahigh concentration of glutathione (GSH) inside tumors destroys reactive oxygen
species (ROS)‐based therapy, improving the outcome of chemodynamic therapy (CDT) …

[HTML][HTML] Advanced nanocarrier-and microneedle-based transdermal drug delivery strategies for skin diseases treatment

F Qu, R Geng, Y Liu, J Zhu - Theranostics, 2022 - ncbi.nlm.nih.gov
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a
global burden and affecting the world economy. Skin diseases severely impact the patients' …