Myeloid cells are pivotal within the immunosuppressive tumour microenvironment. The
accumulation of tumour-modified myeloid cells derived from monocytes or neutrophils …

Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic, aggressive cancer that
frequently progresses and spreads by metastasis to the liver. Cancer-associated fibroblasts …

Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …

Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

The metastasis is a multistep process in which a small proportion of cancer cells are
detached from the colony to enter into blood cells for obtaining a new place for metastasis …

Pancreatic ductal adenocarcinoma is associated with a poor prognosis and there are few
treatment options. The development of immunotherapy in pancreatic ductal adenocarcinoma …

Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Background Although a substantial increase in the survival of patients with other cancers
has been observed in recent decades, pancreatic ductal adenocarcinoma (PDAC) remains …