Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Coumarins are a very large family of compounds containing the unique 2 H-chromen-2-one
motif, as it is known according to IUPAC nomenclature. Coumarin derivatives are widely …

Although the development of mitochondrial therapies has largely focused on diseases
caused by mutations in mitochondrial DNA or in nuclear genes encoding mitochondrial …

Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Hydrogen sulfide (H 2 S) is a ubiquitous small gaseous signaling molecule, playing an
important role in many physiological processes and joining nitric oxide and carbon …

Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Ischemia-reperfusion (IR) injury occurs when blood supply to an organ is disrupted—
ischemia—and then restored—reperfusion—leading to a burst of reactive oxygen species …

Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …