miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses

HA El-Mahdy, AM Mohamadin, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most
frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and mouth …

[HTML][HTML] Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents

M Hashemi, MSA Mirdamadi, Y Talebi… - Pharmacological …, 2023 - Elsevier
The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy

AA Bhat, P Yousuf, NA Wani, A Rizwan… - Signal transduction and …, 2021 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor
prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have …

Overview of oral potentially malignant disorders: from risk factors to specific therapies

L Lorini, C Bescós Atín, S Thavaraj, U Müller-Richter… - Cancers, 2021 - mdpi.com
Simple Summary Oral potentially malignant disorders (OPMDs) include a group of oral
mucosal diseases with different morphological characteristics that are able to progress to …

circFBXO7/miR-96-5p/MTSS1 axis is an important regulator in the Wnt signaling pathway in ovarian cancer

M Wu, Q Qiu, Q Zhou, J Li, J Yang, C Zheng, A Luo… - Molecular Cancer, 2022 - Springer
Background CircRNAs are a novel class of evolutionarily conserved noncoding RNA
molecules that form covalently closed continuous loop structures without 5′ caps and 3 …

The role of biomarkers in HPV-positive head and neck squamous cell carcinoma: towards precision medicine

A Krsek, L Baticic, V Sotosek, T Braut - Diagnostics, 2024 - pmc.ncbi.nlm.nih.gov
Head and neck cancer (HNC) represents a significant global health challenge, with
squamous cell carcinomas (SCCs) accounting for approximately 90% of all HNC cases …

Non-coding RNAs in cancer radiosensitivity: MicroRNAs and lncRNAs as regulators of radiation-induced signaling pathways

M Podralska, S Ciesielska, J Kluiver, A van den Berg… - Cancers, 2020 - mdpi.com
Radiotherapy is a cancer treatment that applies high doses of ionizing radiation to induce
cell death, mainly by triggering DNA double-strand breaks. The outcome of radiotherapy …

Precision medicine approaches to overcome resistance to therapy in head and neck cancers

S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …

[HTML][HTML] EMT imparts cancer stemness and plasticity: new perspectives and therapeutic potential

S Roy, RR Sunkara, MY Parmar, S Shaikh… - Frontiers in Bioscience …, 2020 - imrpress.com
Epithelial-to-mesenchymal transition (EMT) is a fundamental cellular phenomenon that
plays an intrinsic role in development, tissue repair, and cancer progression. EMT is tightly …

Circulating exosomal miR‐96 as a novel biomarker for radioresistant non‐small‐cell lung cancer

Q Zheng, H Ding, L Wang, Y Yan, Y Wan… - Journal of …, 2021 - Wiley Online Library
Patients with non‐small‐cell lung cancer (NSCLC) frequently develop radioresistance,
resulting in poor response to radiation and unfavourable prognosis. Early detection of …