Animal models of atrial fibrillation
D Schüttler, A Bapat, S Kääb, K Lee, P Tomsits… - Circulation …, 2020 - Am Heart Assoc
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in humans and
is a significant source of morbidity and mortality. Despite its prevalence, our mechanistic …
is a significant source of morbidity and mortality. Despite its prevalence, our mechanistic …
Are interactions between epicardial adipose tissue, cardiac fibroblasts and cardiac myocytes instrumental in atrial fibrosis and atrial fibrillation?
A Krishnan, E Chilton, J Raman, P Saxena… - Cells, 2021 - mdpi.com
Atrial fibrillation is very common among the elderly and/or obese. While myocardial fibrosis
is associated with atrial fibrillation, the exact mechanisms within atrial myocytes and …
is associated with atrial fibrillation, the exact mechanisms within atrial myocytes and …
Histological evaluation of cardiac remodelling in equine athletes
Abstract Approximately 1–2 per 100,000 young athletes die from sudden cardiac death
(SCD) and extreme exercise may be associated with myocardial scar and arrhythmias …
(SCD) and extreme exercise may be associated with myocardial scar and arrhythmias …
Vericiguat reduces electrical and structural remodeling in a rabbit model of atrial fibrillation
Q Lou, L Li, G Liu, T Li, L Zhang… - Journal of …, 2023 - journals.sagepub.com
Purpose: The molecular etiology of atrial fibrillation (AF) and its treatment are poorly
understood. AF involves both electrical and structural features. Vericiguat can ameliorate …
understood. AF involves both electrical and structural features. Vericiguat can ameliorate …
Atrial fibrosis and substrate based characterization in atrial fibrillation: time to move forwards
JX Quah, D Dharmaprani, K Tiver… - Journal of …, 2021 - Wiley Online Library
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia in clinical
practice. However, current therapeutic interventions for atrial fibrillation have limited clinical …
practice. However, current therapeutic interventions for atrial fibrillation have limited clinical …
Atrial fibrillation in horses part 1: Pathophysiology
Atrial fibrillation (AF) is the most common clinically relevant arrhythmia in horses, with a
reported prevalence up to 2.5%. The pathophysiology has mainly been investigated in …
reported prevalence up to 2.5%. The pathophysiology has mainly been investigated in …
Electrocardiographic characteristics of trained and untrained standardbred racehorses
SD Nissen, R Weis, EK Krag‐Andersen… - Journal of veterinary …, 2022 - Wiley Online Library
Background Long‐term exercise induces cardiac remodeling that potentially influences the
electrical properties of the heart. Hypothesis/objectives We assessed whether training alters …
electrical properties of the heart. Hypothesis/objectives We assessed whether training alters …
Heart failure, female sex, and atrial fibrillation are the main drivers of human atrial cardiomyopathy: results from the CATCH ME consortium
Background Atrial cardiomyopathy (atCM) is an emerging prognostic factor in cardiovascular
disease. Fibrotic remodeling, cardiomyocyte hypertrophy, and capillary density are …
disease. Fibrotic remodeling, cardiomyocyte hypertrophy, and capillary density are …
Effect of selective IK,ACh inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation
Background and Purpose Inhibition of the G‐protein gated ACh‐activated inward rectifier
potassium current, IK, ACh may be an effective atrial selective treatment strategy for atrial …
potassium current, IK, ACh may be an effective atrial selective treatment strategy for atrial …
JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling
J Winters, ME Von Braunmuhl, S Zeemering… - Scientific reports, 2020 - nature.com
Many cardiac pathologies involve changes in tissue structure. Conventional analysis of
structural features is extremely time-consuming and subject to observer bias. The possibility …
structural features is extremely time-consuming and subject to observer bias. The possibility …