Summary The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019
provides a rules-based synthesis of the available evidence on levels and trends in health …

Executive summary Although health outcomes have improved in low-income and middle-
income countries (LMICs) in the past several decades, a new reality is at hand. Changing …

Disease outbreaks and pandemics have long played a role in societal and economic
change. However, the nature of such change is selective, meaning that it is sometimes …

Background Assessments of age-specific mortality and life expectancy have been done by
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …

Background: With advances in antiretroviral therapy, most deaths in people with HIV are
now attributable to noncommunicable illnesses, especially cardiovascular disease. We …

We aimed to assess global trends in Human Immunodeficiency Virus (HIV)/Acquired
Immune Deficiency Syndrome (AIDS) and evaluate progress toward eradication since the …

Background Detailed assessments of mortality patterns, particularly age-specific mortality,
represent a crucial input that enables health systems to target interventions to specific …

Vector-borne diseases (VBDs), including malaria, dengue and leishmaniasis, cause
considerable morbidity and mortality in tropical regions of the world. Vector control methods …

Rationale: Reducing the global burden of sepsis, a recognized global health challenge,
requires comprehensive data on the incidence and mortality on a global scale. Objectives …

Background Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and
monitoring the progress of prevention and control efforts in countries. We provide a …