There is an immediate need to drastically reduce the emissions associated with global fossil
fuel consumption in order to limit climate change. However, carbon-based materials …

The biosynthesis of the solvents 1-butanol and acetone is restricted to species of the genus
Clostridium, a diverse group of Gram-positive, endospore forming anaerobes comprising …

Solventogenic clostridia are important industrial microorganisms that produce various
chemicals and fuels. Effective genetic tools would facilitate physiological studies aimed both …

Six bacterial genomes, Geobacter metallireducens GS-15, Chromohalobacter salexigens,
Vibrio breoganii 1C-10, Bacillus cereus ATCC 10987, Campylobacter jejuni subsp. jejuni 81 …

Clostridium species are both heroes and villains. Some cause serious human and animal
diseases, those present in the gut microbiota generally contribute to health and wellbeing …

Mobile group II introns are bacterial retrotransposons that combine the activities of an
autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert …

Genetic transformation of bacteria harboring multiple Restriction-Modification (RM) systems
is often difficult using conventional methods. Here, we describe a mimicking-of-DNA …

Clostridium organisms are of major importance in the development of technologies to
produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass …

The discovery and exploitation of the prokaryotic adaptive immunity system based on
clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR …

Bacterial natural products have found many important industrial applications. Yet traditional
discovery pipelines often prioritize individual natural product families despite the presence …