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Revolutionizing biosensing with superwettability: Designs, mechanisms, and applications
Interfacial superwettability and biosensors are constantly evolving and being recognized as
ubiquitous components of interfacial science. Superwettability provides new insight from …
ubiquitous components of interfacial science. Superwettability provides new insight from …
Digital Microfluidics for Sample Preparation in Low‐Input Proteomics
MK Steinbach, J Leipert, T Matzanke… - Small Methods, 2025 - Wiley Online Library
Low‐input proteomics, also referred to as micro‐or nanoproteomics, has become
increasingly popular as it allows one to elucidate molecular processes in rare biological …
increasingly popular as it allows one to elucidate molecular processes in rare biological …
Diversity of post-translational modifications and cell signaling revealed by single cell and single organelle mass spectrometry
The rapid evolution of mass spectrometry-based single-cell proteomics now enables the
cataloging of several thousand proteins from single cells. We investigated whether we could …
cataloging of several thousand proteins from single cells. We investigated whether we could …
Map** Nanoscale‐To‐Single‐Cell Phosphoproteomic Landscape by Chip‐DIA
Protein phosphorylation plays a crucial role in regulating disease phenotypes and serves as
a key target for drug development. Map** nanoscale‐to‐single‐cell samples can unravel …
a key target for drug development. Map** nanoscale‐to‐single‐cell samples can unravel …
Optimization of microfluidics for point-of-care blood sensing
A Tavakolidakhrabadi, M Stark, U Bacher, M Legros… - Biosensors, 2024 - mdpi.com
Blood tests are widely used in modern medicine to diagnose certain illnesses and evaluate
the overall health of a patient. To enable testing in resource-limited areas, there has been …
the overall health of a patient. To enable testing in resource-limited areas, there has been …
Proteomics-on-a-Chip–Microfluidics Meets Proteomics
Proteomics provides an understanding of biological systems by enabling the detailed study
of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic …
of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic …
Comparative proteomic landscapes elucidate human preimplantation development and failure
W Zhu, J Meng, Y Li, L Gu, W Liu, Z Li, Y Shen, X Shen… - Cell, 2025 - cell.com
Understanding mammalian preimplantation development, particularly in humans, at the
proteomic level remains limited. Here, we applied our comprehensive solution of …
proteomic level remains limited. Here, we applied our comprehensive solution of …
[HTML][HTML] Droplet-Based Microfluidics with Mass Spectrometry for Microproteomics
Microproteomics, the profiling of protein expressions in small cell populations or individual
cells, is essential for understanding complex biological systems. However, sample loss and …
cells, is essential for understanding complex biological systems. However, sample loss and …
A single microfluidic device for multi-omics analysis sample preparation
Combining different “omics” approaches, such as genomics and proteomics, is necessary to
generate a detailed and complete insight into microbiome comprehension. Proper sample …
generate a detailed and complete insight into microbiome comprehension. Proper sample …
Advancements in Global Phosphoproteomics Profiling: Overcoming Challenges in Sensitivity and Quantification
G Muneer, CS Chen, YJ Chen - Proteomics, 2025 - Wiley Online Library
Protein phosphorylation introduces post‐genomic diversity to proteins, which plays a crucial
role in various cellular activities. Elucidation of system‐wide signaling cascades requires …
role in various cellular activities. Elucidation of system‐wide signaling cascades requires …