Revolutionizing biosensing with superwettability: Designs, mechanisms, and applications

ZF Gao, H Zhu, Y Li, X Yang, X Ren, D Wu, H Ma… - Nano Today, 2023 - Elsevier
Interfacial superwettability and biosensors are constantly evolving and being recognized as
ubiquitous components of interfacial science. Superwettability provides new insight from …

Digital Microfluidics for Sample Preparation in Low‐Input Proteomics

MK Steinbach, J Leipert, T Matzanke… - Small Methods, 2025 - Wiley Online Library
Low‐input proteomics, also referred to as micro‐or nanoproteomics, has become
increasingly popular as it allows one to elucidate molecular processes in rare biological …

Diversity of post-translational modifications and cell signaling revealed by single cell and single organelle mass spectrometry

DG Mun, FA Bhat, N Joshi, L Sandoval, H Ding… - Communications …, 2024 - nature.com
The rapid evolution of mass spectrometry-based single-cell proteomics now enables the
cataloging of several thousand proteins from single cells. We investigated whether we could …

Map** Nanoscale‐To‐Single‐Cell Phosphoproteomic Landscape by Chip‐DIA

G Muneer, ST Gebreyesus, CS Chen, TT Lee… - Advanced …, 2025 - Wiley Online Library
Protein phosphorylation plays a crucial role in regulating disease phenotypes and serves as
a key target for drug development. Map** nanoscale‐to‐single‐cell samples can unravel …

Optimization of microfluidics for point-of-care blood sensing

A Tavakolidakhrabadi, M Stark, U Bacher, M Legros… - Biosensors, 2024 - mdpi.com
Blood tests are widely used in modern medicine to diagnose certain illnesses and evaluate
the overall health of a patient. To enable testing in resource-limited areas, there has been …

Proteomics-on-a-Chip–Microfluidics Meets Proteomics

H Zhang, L Zhao, J Brodský, L Migliaccio… - Biosensors and …, 2025 - Elsevier
Proteomics provides an understanding of biological systems by enabling the detailed study
of protein expression profiles, which is crucial for early disease diagnosis. Microfluidic …

Comparative proteomic landscapes elucidate human preimplantation development and failure

W Zhu, J Meng, Y Li, L Gu, W Liu, Z Li, Y Shen, X Shen… - Cell, 2025 - cell.com
Understanding mammalian preimplantation development, particularly in humans, at the
proteomic level remains limited. Here, we applied our comprehensive solution of …

[HTML][HTML] Droplet-Based Microfluidics with Mass Spectrometry for Microproteomics

H Li, Y Ma, R Fu, J Peng, Y Zhai, J Li, W Xu, S Hu… - Engineering, 2024 - Elsevier
Microproteomics, the profiling of protein expressions in small cell populations or individual
cells, is essential for understanding complex biological systems. However, sample loss and …

A single microfluidic device for multi-omics analysis sample preparation

RKR Kumar, I Haddad, MM Ndiaye, M Marbouty… - Lab on a Chip, 2025 - pubs.rsc.org
Combining different “omics” approaches, such as genomics and proteomics, is necessary to
generate a detailed and complete insight into microbiome comprehension. Proper sample …

Advancements in Global Phosphoproteomics Profiling: Overcoming Challenges in Sensitivity and Quantification

G Muneer, CS Chen, YJ Chen - Proteomics, 2025 - Wiley Online Library
Protein phosphorylation introduces post‐genomic diversity to proteins, which plays a crucial
role in various cellular activities. Elucidation of system‐wide signaling cascades requires …