Transforming growth factor-β in stem cells and tissue homeostasis
Abstract TGF-β 1–3 are unique multi-functional growth factors that are only expressed in
mammals, and mainly secreted and stored as a latent complex in the extracellular matrix …
mammals, and mainly secreted and stored as a latent complex in the extracellular matrix …
Regulation of TGF-β family signaling by inhibitory Smads
K Miyazawa, K Miyazono - Cold Spring Harbor …, 2017 - cshperspectives.cshlp.org
Inhibitory Smads (I-Smads) have conserved carboxy-terminal MH2 domains but highly
divergent amino-terminal regions when compared with receptor-regulated Smads (R …
divergent amino-terminal regions when compared with receptor-regulated Smads (R …
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model
INTRODUCTION Alzheimer's disease (AD) is the most common form of age-related
dementia, characterized by cognitive impairment, neurodegeneration, β-amyloid (Aβ) …
dementia, characterized by cognitive impairment, neurodegeneration, β-amyloid (Aβ) …
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
HD Schmidt, RS Duman - Behavioural pharmacology, 2007 - journals.lww.com
Major depressive disorder (MDD) is characterized by structural and neurochemical changes
in limbic structures, including the hippocampus, that regulate mood and cognitive functions …
in limbic structures, including the hippocampus, that regulate mood and cognitive functions …
Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action
Adult hippocampal neurogenesis, a once unorthodox concept, has changed into one of the
most rapidly growing fields in neuroscience. The present report results from the ECNP …
most rapidly growing fields in neuroscience. The present report results from the ECNP …
Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish
JR Lenkowski, PA Raymond - Progress in retinal and eye research, 2014 - Elsevier
Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …
It takes a village: constructing the neurogenic niche
CS Bjornsson, M Apostolopoulou, Y Tian, S Temple - Developmental cell, 2015 - cell.com
Although many features of neurogenesis during development and in the adult are intrinsic to
the neurogenic cells themselves, the role of the microenvironment is irrefutable. The …
the neurogenic cells themselves, the role of the microenvironment is irrefutable. The …
Microglia phenotype diversity
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting
phenotype that is characterized by a ramified morphology. With their fine processes …
phenotype that is characterized by a ramified morphology. With their fine processes …
Regulation of adult neurogenesis and plasticity by (early) stress, glucocorticoids, and inflammation
PJ Lucassen, CA Oomen… - Cold Spring …, 2015 - cshperspectives.cshlp.org
Exposure to stress is one of the best-known negative regulators of adult neurogenesis (AN).
We discuss changes in neurogenesis in relation to exposure to stress, glucocorticoid …
We discuss changes in neurogenesis in relation to exposure to stress, glucocorticoid …
Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes
P Ashwood, A Enstrom, P Krakowiak… - Journal of …, 2008 - Elsevier
Autism spectrum disorders (ASD) are characterized by impairment in social interactions,
communication deficits, and restricted repetitive interests and behaviors. There is evidence …
communication deficits, and restricted repetitive interests and behaviors. There is evidence …