Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
Pathogenesis of respiratory viral and fungal coinfections
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for develo** invasive fungal infections. Influenza virus is one of the most …
“at risk” groups for develo** invasive fungal infections. Influenza virus is one of the most …
A distinct function of regulatory T cells in tissue protection
Regulatory T (Treg) cells suppress immune responses to a broad range of non-microbial
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
[HTML][HTML] Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions
MJ Bunders, M Altfeld - Immunity, 2020 - cell.com
Men present more frequently with severe manifestations of coronavirus disease 2019
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …
Influenza virus-induced lung injury: pathogenesis and implications for treatment
S Herold, C Becker, KM Ridge… - European Respiratory …, 2015 - Eur Respiratory Soc
The influenza viruses are some of the most important human pathogens, causing substantial
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …
Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
M Khatri, LA Richardson, T Meulia - Stem cell research & therapy, 2018 - Springer
Background Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
Host recovery from respiratory viral infection
Emerging and re-emerging respiratory viral infections pose a tremendous threat to human
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection
JW Griffith, LD Faustino, VI Cottrell, K Nepal… - Nature …, 2023 - nature.com
Regulatory T (Treg) cell modulation of adaptive immunity and tissue homeostasis is well
described; however, less is known about Treg cell-mediated regulation of the innate immune …
described; however, less is known about Treg cell-mediated regulation of the innate immune …
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
Memory CD8+ T cells are critical for host defense upon reexposure to intracellular
pathogens. We found that interleukin 10 (IL-10) derived from CD4+ regulatory T cells (Treg …
pathogens. We found that interleukin 10 (IL-10) derived from CD4+ regulatory T cells (Treg …
Dynamic natural killer cell and T cell responses to influenza infection
Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit
their spread, but they do not prevent all infections. Therapeutic treatments for those …
their spread, but they do not prevent all infections. Therapeutic treatments for those …