SLC6 neurotransmitter transporters: structure, function, and regulation
AS Kristensen, J Andersen, TN Jørgensen… - Pharmacological …, 2011 - Elsevier
The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
Mechanisms of dopamine transporter regulation in normal and disease states
The dopamine (DA) transporter (DAT) controls the spatial and temporal dynamics of DA
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …
Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings
WJ Panenka, RM Procyshyn, T Lecomte… - Drug and alcohol …, 2013 - Elsevier
Methamphetamine (MA) is a highly addictive psychostimulant drug that principally affects the
monoamine neurotransmitter systems of the brain and results in feelings of alertness …
monoamine neurotransmitter systems of the brain and results in feelings of alertness …
How addictive drugs disrupt presynaptic dopamine neurotransmission
D Sulzer - Neuron, 2011 - cell.com
The fundamental principle that unites addictive drugs appears to be that each enhances
synaptic dopamine by means that dissociate it from normal behavioral control, so that they …
synaptic dopamine by means that dissociate it from normal behavioral control, so that they …
Amphetamines, new psychoactive drugs and the monoamine transporter cycle
In monoaminergic neurons, the vesicular transporters and the plasma membrane
transporters operate in a relay. Amphetamine and its congeners target this relay to elicit their …
transporters operate in a relay. Amphetamine and its congeners target this relay to elicit their …
Spatial contextual recognition memory updating is modulated by dopamine release in the dorsal hippocampus from the locus coeruleus
DK Gálvez-Márquez… - Proceedings of the …, 2022 - National Acad Sciences
Detecting novelty is critical to consolidate declarative memories, such as spatial contextual
recognition memory. It has been shown that stored memories, when retrieved, are …
recognition memory. It has been shown that stored memories, when retrieved, are …
SLC6 transporters: structure, function, regulation, disease association and therapeutics
The SLC6 family of secondary active transporters are integral membrane solute carrier
proteins characterized by the Na+-dependent translocation of small amino acid or amino …
proteins characterized by the Na+-dependent translocation of small amino acid or amino …
Dopamine reuptake and inhibitory mechanisms in human dopamine transporter
Y Li, X Wang, Y Meng, T Hu, J Zhao, R Li, Q Bai… - Nature, 2024 - nature.com
The dopamine transporter has a crucial role in regulation of dopaminergic
neurotransmission by uptake of dopamine into neurons and contributes to the abuse …
neurotransmission by uptake of dopamine into neurons and contributes to the abuse …
Regulation of the dopamine and vesicular monoamine transporters: pharmacological targets and implications for disease
CL German, MG Baladi, LM McFadden… - Pharmacological …, 2015 - Elsevier
Dopamine (DA) plays a well recognized role in a variety of physiologic functions such as
movement, cognition, mood, and reward. Consequently, many human disorders are due, in …
movement, cognition, mood, and reward. Consequently, many human disorders are due, in …
Targeting SLC transporters: small molecules as modulators and therapeutic opportunities
Solute carrier (SLCs) transporters mediate the transport of a broad range of solutes across
biological membranes. Dysregulation of SLCs has been associated with various …
biological membranes. Dysregulation of SLCs has been associated with various …