Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour

J LeDoux, ND Daw - Nature Reviews Neuroscience, 2018 - nature.com
Research on defensive behaviour in mammals has in recent years focused on elicited
reactions; however, organisms also make active choices when responding to danger. We …

Coming to terms with fear

JE LeDoux - Proceedings of the National Academy of Sciences, 2014 - pnas.org
The brain mechanisms of fear have been studied extensively using Pavlovian fear
conditioning, a procedure that allows exploration of how the brain learns about and later …

Projections from neocortex mediate top-down control of memory retrieval

P Rajasethupathy, S Sankaran, JH Marshel, CK Kim… - Nature, 2015 - nature.com
Top-down prefrontal cortex inputs to the hippocampus have been hypothesized to be
important in memory consolidation, retrieval, and the pathophysiology of major psychiatric …

Dendritic inhibition in the hippocampus supports fear learning

M Lovett-Barron, P Kaifosh, MA Kheirbek, N Danielson… - Science, 2014 - science.org
Fear memories guide adaptive behavior in contexts associated with aversive events. The
hippocampus forms a neural representation of the context that predicts aversive events …

Integrated cardio-behavioral responses to threat define defensive states

J Signoret-Genest, N Schukraft, S L. Reis… - Nature …, 2023 - nature.com
Fear and anxiety are brain states that evolved to mediate defensive responses to threats.
The defense reaction includes multiple interacting behavioral, autonomic and endocrine …

[PDF][PDF] Emotion: Clues from the brain

JE LeDoux - Annual review of psychology, 1995 - gruberpeplab.com
Despite the obvious importance of emotion to human existence, scientists concerned with
human nature have not been able to reach a consensus about what emotion is and what …

Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex

RN Cardinal, JA Parkinson, J Hall, BJ Everitt - … & Biobehavioral Reviews, 2002 - Elsevier
Emotions are multifaceted, but a key aspect of emotion involves the assessment of the value
of environmental stimuli. This article reviews the many psychological representations …

[SÁCH][B] Domjan and Burkhard's" The principles of learning and behavior"

M Domjan - 1993 - psycnet.apa.org
The aim of the third edition of this book is... to provide a lucid introduction to contemporary
phenomena and theories about learning and behavior. The book strives to present a …

Conditional and unconditional components of aversively motivated freezing, flight and darting in mice

JM Trott, AN Hoffman, I Zhuravka, MS Fanselow - Elife, 2022 - elifesciences.org
Fear conditioning is one of the most frequently used laboratory procedures for modeling
learning and memory generally, and anxiety disorders in particular. The conditional …

Fear conditioning induces associative long-term potentiation in the amygdala

MT Rogan, UV Stäubli, JE LeDoux - Nature, 1997 - nature.com
Long-term potentiation (LTP) is an experience-dependent form of neural plasticity believed
to involve mechanisms that underlie memory formation,,. LTP has been studied most …