Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Risk factors for childhood obesity in the first 1,000 days: a systematic review

JAW Baidal, LM Locks, ER Cheng… - American journal of …, 2016 - Elsevier
Context Mounting evidence suggests that the origins of childhood obesity and related
disparities can be found as early as the “first 1,000 days”—the period from conception to age …

Environmental pollutants and child health—A review of recent concerns

M Vrijheid, M Casas, M Gascon, D Valvi… - International journal of …, 2016 - Elsevier
In recent years, many new studies have evaluated associations between environmental
pollutants and child health. This review aims to provide a broad summary of this literature …

Chlorinated persistent organic pollutants, obesity, and type 2 diabetes

DH Lee, M Porta, DR Jacobs Jr… - Endocrine …, 2014 - academic.oup.com
Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …

[HTML][HTML] Oxidative stress in NAFLD: role of nutrients and food contaminants

C Rives, A Fougerat, S Ellero-Simatos, N Loiseau… - Biomolecules, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

[HTML][HTML] Exposure to perfluoroalkyl substances (PFAS) and dyslipidemia, hypertension and obesity in adolescents. The Fit Futures study

M Averina, J Brox, S Huber, AS Furberg - Environmental research, 2021 - Elsevier
Background Prevalence of obesity, hypertension and dyslipidemia has been increasing in
children and adolescents worldwide. Exposure to environmental pollutants may contribute to …

Ancestral dichlorodiphenyltrichloroethane (DDT) exposure promotes epigenetic transgenerational inheritance of obesity

MK Skinner, M Manikkam, R Tracey… - BMC medicine, 2013 - Springer
Background Ancestral environmental exposures to a variety of environmental factors and
toxicants have been shown to promote the epigenetic transgenerational inheritance of adult …

Environmental obesogens and their impact on susceptibility to obesity: new mechanisms and chemicals

RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed
worldwide. There is a growing need to understand all the factors that contribute to obesity to …

Association of prenatal exposure to endocrine-disrupting chemicals with liver injury in children

V Midya, E Colicino, DV Conti, K Berhane… - JAMA Network …, 2022 - jamanetwork.com
Importance Prenatal exposures to endocrine-disrupting chemicals (EDCs) may increase the
risk for liver injury in children; however, human evidence is scarce, and previous studies …