Antibiotics in early life: dysbiosis and the damage done

H Neuman, P Forsythe, A Uzan, O Avni… - FEMS microbiology …, 2018 - academic.oup.com
Antibiotics are the most common type of medication prescribed to children, including infants,
in the Western world. While use of antibiotics has transformed previously lethal infections …

Maternal-infant antibiotic resistance genes transference: what do we know?

A Samarra, M Esteban-Torres, R Cabrera-Rubio… - Gut …, 2023 - Taylor & Francis
Resistance to antibiotics is becoming a worldwide threat as infections caused by multidrug-
resistant pathogenic microorganisms can overcome antibiotic treatments and spread quickly …

Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome

AJ Gasparrini, B Wang, X Sun, EA Kennedy… - Nature …, 2019 - nature.com
Hospitalized preterm infants receive frequent and often prolonged exposures to antibiotics
because they are vulnerable to infection. It is not known whether the short-term effects of …

[HTML][HTML] Microbiota supplementation with Bifidobacterium and Lactobacillus modifies the preterm infant gut microbiota and metabolome: an observational study

C Alcon-Giner, MJ Dalby, S Caim, J Ketskemety… - Cell Reports …, 2020 - cell.com
Supplementation with members of the early-life microbiota as" probiotics" is increasingly
used in attempts to beneficially manipulate the preterm infant gut microbiota. We performed …

Combined effects of micro-/nano-plastics and oxytetracycline on the intestinal histopathology and microbiome in zebrafish (Danio rerio)

Z Yu, L Zhang, Q Huang, S Dong, X Wang… - Science of the Total …, 2022 - Elsevier
Accumulated evidence has demonstrated that microplastics and oxytetracycline (OTC) affect
organisms, but few studies have investigated their combined effects on aquatic organisms …

Antibiotics disturb the microbiome and increase the incidence of resistance genes in the gut of a common soil collembolan

D Zhu, XL An, QL Chen, XR Yang… - … science & technology, 2018 - ACS Publications
Gut microbiota make an important contribution to host health but the effects of environmental
pressures on the gut microbiota of soil fauna are largely uncharacterized. Here, we examine …

[HTML][HTML] Sub-chronic exposure to antibiotics doxycycline, oxytetracycline or florfenicol impacts gut barrier and induces gut microbiota dysbiosis in adult zebrafish …

M Qian, J Wang, X Ji, H Yang, B Tang, H Zhang… - Ecotoxicology and …, 2021 - Elsevier
Antibiotics are widely used in the treatment of bacterial infections and as food additives in
the livestock industry. The wide usage of antibiotics causes residues in animal products, like …

Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria

G Casaburi, RM Duar, DP Vance, R Mitchell… - … Resistance & Infection …, 2019 - Springer
Background Antibiotic-resistant (AR) bacteria are a global threat. AR bacteria can be
acquired in early life and have long-term sequelae. Limiting the spread of antibiotic …

Effects of probiotic supplementation on the gut microbiota and antibiotic resistome development in preterm infants

E Esaiassen, E Hjerde, JP Cavanagh… - Frontiers in …, 2018 - frontiersin.org
Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and
Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care …

Abundance and diversity of resistomes differ between healthy human oral cavities and gut

VR Carr, EA Witherden, S Lee, S Shoaie… - Nature …, 2020 - nature.com
The global threat of antimicrobial resistance has driven the use of high-throughput
sequencing techniques to monitor the profile of resistance genes, known as the resistome, in …