Sociotechnical safeguards for genomic data privacy

Z Wan, JW Hazel, EW Clayton, Y Vorobeychik… - Nature Reviews …, 2022‏ - nature.com
Recent developments in a variety of sectors, including health care, research and the direct-
to-consumer industry, have led to a dramatic increase in the amount of genomic data that …

[HTML][HTML] Investigative genetic genealogy: Current methods, knowledge and practice

D Kling, C Phillips, D Kennett, A Tillmar - Forensic Science International …, 2021‏ - Elsevier
Investigative genetic genealogy (IGG) has emerged as a new, rapidly growing field of
forensic science. We describe the process whereby dense SNP data, commonly comprising …

[HTML][HTML] Forensic genealogy, bioethics and the Golden State Killer case

RA Wickenheiser - Forensic science international: Synergy, 2019‏ - Elsevier
A case study will be used to examine specific issues of bioethics and forensic science that
occur in forensic investigative genealogical searching, which include genetic privacy …

Pedigrees and perpetrators: uses of DNA and genealogy in forensic investigations

SH Katsanis - Annual review of genomics and human genetics, 2020‏ - annualreviews.org
In the past few years, cases with DNA evidence that could not be solved with direct matches
in DNA databases have benefited from comparing single-nucleotide polymorphism data with …

A reference haplotype panel for genome-wide imputation of short tandem repeats

S Saini, I Mitra, N Mousavi, SF Fotsing… - Nature …, 2018‏ - nature.com
Short tandem repeats (STRs) are involved in dozens of Mendelian disorders and have been
implicated in complex traits. However, genoty** arrays used in genome-wide association …

Attacks on genetic privacy via uploads to genealogical databases

MD Edge, G Coop - Elife, 2020‏ - elifesciences.org
Direct-to-consumer (DTC) genetics services are increasingly popular, with tens of millions of
customers. Several DTC genealogy services allow users to upload genetic data to search for …

[HTML][HTML] Considerations for genomic data privacy and security when working in the cloud

AB Carter - The Journal of Molecular Diagnostics, 2019‏ - Elsevier
Next-generation sequencing produces large amounts of data. The complexity and data
management issues associated with next-generation sequencing have led many …

Associations between forensic loci and expression levels of neighboring genes may compromise medical privacy

MM Bañuelos, YJA Zavaleta, A Roldan… - Proceedings of the …, 2022‏ - pnas.org
A set of 20 short tandem repeats (STRs) is used by the US criminal justice system to identify
suspects and to maintain a database of genetic profiles for individuals who have been …

Global patterns of STR sequence variation: sequencing the CEPH human genome diversity panel for 58 forensic STRs using the Illumina ForenSeq DNA Signature …

C Phillips, L Devesse, D Ballard, L van Weert… - …, 2018‏ - Wiley Online Library
The 944 individuals of the CEPH human genome diversity panel (HGDP–CEPH), a standard
sample set of 51 globally distributed populations, were sequenced using the Illumina …

Using game theory to thwart multistage privacy intrusions when sharing data

Z Wan, Y Vorobeychik, W **a, Y Liu, M Wooders… - Science …, 2021‏ - science.org
Person-specific biomedical data are now widely collected, but its sharing raises privacy
concerns, specifically about the re-identification of seemingly anonymous records. Formal re …