Isocyanide-based multicomponent reactions for the synthesis of benzopyran derivatives with biological scaffolds
Benzopyrans (BZPs) are one of the most privileged and influential small O-heterocycles that
form the core of many natural compounds, commercial drugs, biological compositions …
form the core of many natural compounds, commercial drugs, biological compositions …
Dual active 1, 4-dihydropyridine derivatives: Design, green synthesis and in vitro anti-cancer and anti-oxidant studies
P Anaikutti, P Makam - Bioorganic Chemistry, 2020 - Elsevier
The present work describes the design of 1, 4-dihydropyridines (1, 4-DHPs) with diverse
variations in structural and functional groups. The physico-chemical properties and drug-like …
variations in structural and functional groups. The physico-chemical properties and drug-like …
Indolyl-4H-chromenes: Multicomponent one-pot green synthesis, in vitro and in silico, anticancer and antioxidant studies
The present work describes the simple, economical and eco-friendly multicomponent one-
pot synthesis of indolyl-4H-chromene derivatives. It is being achieved by reacting …
pot synthesis of indolyl-4H-chromene derivatives. It is being achieved by reacting …
[HTML][HTML] Antibacterial and antioxidant potential of GC-MS analysis of crude ethyl acetate extract from the tropical mangrove plant Avicennia officinalis L.
Avicennia officinalis L. is an important mangrove plant used in traditional medicine to treat
various diseases like asthma, dyspepsia, paralysis, tumor and rheumatism in aboriginal …
various diseases like asthma, dyspepsia, paralysis, tumor and rheumatism in aboriginal …
Synthesis, in vitro, in silico and DFT studies of indole curcumin derivatives as potential anticancer agents
The curcumin derivatives were synthesized for the first time using simple starting materials
through a three-component reaction, yielding high purity compounds. The synthesized …
through a three-component reaction, yielding high purity compounds. The synthesized …
Iodine catalyzed synthesis of imidazo [1, 2-a] pyrazine and imidazo [1, 2-a] pyridine derivatives and their anticancer activity
R Krishnamoorthy, P Anaikutti - RSC advances, 2023 - pubs.rsc.org
An efficient iodine-catalyzed method for synthesizing imidazo [1, 2-a] pyrazines and imidazo
[1, 2-a] pyridines via one-pot three-component condensations has been reported. The …
[1, 2-a] pyridines via one-pot three-component condensations has been reported. The …
Green synthesis of gold nanoparticles using quercetin biomolecule from mangrove plant, Ceriops tagal: Assessment of antiproliferative properties, cellular uptake and …
Synthesis, structural elucidation and in vitro cytotoxic properties of quercetin gold
nanoparticles (Qu-AuNPs) were derived from the mangrove plant, Ceriops tagal. UV–Visible …
nanoparticles (Qu-AuNPs) were derived from the mangrove plant, Ceriops tagal. UV–Visible …
A comprehensive in silico and in vitro studies on quinizarin: a promising phytochemical derived from Rhizophora mucronata Lam
Mangrove plants are a great source of phytomedicines, since from the beginning of human
civilization and the origin of traditional medicines. In the present study, ten different …
civilization and the origin of traditional medicines. In the present study, ten different …
Anticancer activities, molecular docking and structure–activity relationship of novel synthesized 4H-chromene, and 5H-chromeno[2,3-d]pyrimidine candidates
In the present study, a series of 4 H-chromene and 5 H-chromeno [2, 3-d] pyrimidine
derivatives was synthesized and evaluated as potential cytotoxic agents. The cytotoxic …
derivatives was synthesized and evaluated as potential cytotoxic agents. The cytotoxic …
Synthesis, in vitro and in silico antimalarial activity of 7-chloroquinoline and 4H-chromene conjugates
A new series of chloroquinoline-4H-chromene conjugates incorporating piperizine or
azipane tethers were synthesized and their anti-malarial activity were evaluated against two …
azipane tethers were synthesized and their anti-malarial activity were evaluated against two …