Improved model systems to predict drug efficacy, interactions, and drug-induced kidney
injury (DIKI) are crucially needed in drug development. Organ-on-a-chip technology is a …

The application of microbial co-cultures is now recognized in the fields of biotechnology,
ecology, and medicine. Understanding the biological interactions that govern the …

The tumor microenvironment (TME) is a complex heterogeneous assembly composed of a
variety of cell types and physical features. One such feature, hypoxia, is associated with …

The lymph node is a structurally complex organ of the immune system, whose dynamic
cellular arrangements are thought to control much of human health. Currently, no methods …

Although, the precise molecular mechanisms underlying Parkinson's disease (PD) are still
elusive, it is now known that spreading of alpha-synuclein (aSyn) pathology and …

Cell–cell communication is a crucial component of many biological functions. For example,
understanding how immune cells and cancer cells interact, both at the immunological …

The urinary system, comprising the kidneys, ureters, bladder, and urethra, has a unique
mechanical and fluid microenvironment, which is essential to the urinary system growth and …

This review aims to propose the integrative implementation of microfluidic devices,
biomaterials, and computational methods that can lead to a significant progress in tissue …

Motivation The interactions among various types of cells play critical roles in cell functions
and the maintenance of the entire organism. While cell–cell interactions are traditionally …

Oxygen plays a key role in stem cell biology as a signaling molecule and as an indicator of
cell energy metabolism. Quantification of cellular oxygen kinetics, ie the determination of …