Antibody–drug conjugates (ADCs) are one of the fastest growing classes of oncology
therapeutics. After half a century of research, the approvals of brentuximab vedotin (in 2011) …

Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are
widely used in the identification and detection of cell makers, serum analytes, and …

Since the introduction of modern capillary electrophoresis (CE) by Jorgenson and Lukacs in
1981, CE has evolved into a highly mature and versatile separation technique. After a first …

Charge sensitive separation methods such as ion exchange chromatography (CEX) and
capillary electrophoresis (CE) have recently been coupled to mass spectrometry to facilitate …

This review article describes the significant recent advances in the analysis of proteins by
capillary and microchip electrophoresis during the period from mid-2014 to early 2017. This …

Capillary electrophoresis (CE), after being introduced several decades ago, has carved out
a niche for itself in the field of analytical characterization of biopharmaceutical products. It …

Monoclonal antibodies (mAbs) and their related products as antibody-drug-conjugates
(ADCs) or biosimilars represent a constantly growing class of molecules therapeutic proteins …

The immunoglobulin degrading enzyme from Streptococcus pyogenes, IdeS, was
discovered as a mechanism by which pathogenic bacteria circumvent antibody mediated …

Out of all categories, monoclonal antibodies (mAbs), biosimilar, antibody-drug conjugates
(ADCs) and Fc-fusion proteins attract the most interest due to their strong therapeutic …

This review focuses on the latest development of microseparation electromigration methods
in capillaries and microfluidic devices coupled with MS for detection and identification of …