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Oxidative stress in obstructive sleep apnea and intermittent hypoxia–revisited–the bad ugly and good: implications to the heart and brain
L Lavie - Sleep medicine reviews, 2015 - Elsevier
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …
Therapeutic potential of intermittent hypoxia: a matter of dose
A Navarrete-Opazo, GS Mitchell - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …
triggers a bewildering array of both detrimental and beneficial effects in multiple …
Therapeutic acute intermittent hypoxia: A translational roadmap for spinal cord injury and neuromuscular disease
We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …
strategy to improve respiratory and non-respiratory motor function in people with …
Unexpected benefits of intermittent hypoxia: enhanced respiratory and nonrespiratory motor function
Intermittent hypoxia (IH) is most often thought of for its role in morbidity associated with sleep-
disordered breathing, including central nervous system pathology. However, recent …
disordered breathing, including central nervous system pathology. However, recent …
Intermittent hypoxia and neurorehabilitation
In recent years, it has become clear that brief, repeated presentations of hypoxia [ie, acute
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …
Intermittent hypoxia: a low-risk research tool with therapeutic value in humans
JH Mateika, M El-Chami… - Journal of applied …, 2015 - journals.physiology.org
Intermittent hypoxia has generally been perceived as a high-risk stimulus, particularly in the
field of sleep medicine, because it is thought to initiate detrimental cardiovascular …
field of sleep medicine, because it is thought to initiate detrimental cardiovascular …
Acute intermittent hypoxia enhances corticospinal synaptic plasticity in humans
Acute intermittent hypoxia (AIH) enhances voluntary motor output in humans with central
nervous system damage. The neural mechanisms contributing to these beneficial effects are …
nervous system damage. The neural mechanisms contributing to these beneficial effects are …
Respiratory neuroplasticity: Mechanisms and translational implications of phrenic motor plasticity
GS Mitchell, TL Baker - Handbook of Clinical Neurology, 2022 - Elsevier
Widespread appreciation that neuroplasticity is an essential feature of the neural system
controlling breathing has emerged only in recent years. In this chapter, we focus on …
controlling breathing has emerged only in recent years. In this chapter, we focus on …
Daily acute intermittent hypoxia elicits functional recovery of diaphragm and inspiratory intercostal muscle activity after acute cervical spinal injury
A Navarrete-Opazo, S Vinit, BJ Dougherty… - Experimental …, 2015 - Elsevier
A major cause of mortality after spinal cord injury is respiratory failure. In normal rats, acute
intermittent hypoxia (AIH) induces respiratory motor plasticity, expressed as diaphragm (Dia) …
intermittent hypoxia (AIH) induces respiratory motor plasticity, expressed as diaphragm (Dia) …
Single-session effects of acute intermittent hypoxia on breathing function after human spinal cord injury
T Sutor, K Cavka, AK Vose, JF Welch, P Davenport… - Experimental …, 2021 - Elsevier
After spinal cord injury (SCI) respiratory complications are a leading cause of morbidity and
mortality. Acute intermittent hypoxia (AIH) triggers spinal respiratory motor plasticity in rodent …
mortality. Acute intermittent hypoxia (AIH) triggers spinal respiratory motor plasticity in rodent …